Protein
tRNA wybutosine-synthesizing protein 2/3/4
Organism
Oryza sativa subsp. japonica
Function
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity).
Similarity
In the N-terminal section; belongs to the TYW3 family.
Sequence
MEFDRRKAAALAALASPAPDKSPKGGVDAPIAPLLDALNSHPDLFTTSSCSGRVSVLAQPPPPQQADPGGAKTKKKARGGGWVYISHDPADPEALVEVLFGVKEGGGGGDDELVFRFEPMIVAVECRDAAAAAALVAAAVGAGFRESGITSLQKRVMVALRCSIRMEVPLGQTKELVVSPDYIRYLVRIANSKMEANKKRMGGFLDLLQAKISLEASYLESQDPVLQNGAKHGFGNAKRHVLISLSFYPAFISPHGVILTQEEALPTLSGNTTHCLSTAALEITGEPIEKLFLWGQSACALTVGREHHILTFGGFGGPGRHARRNYSLLVNPGSGLLTELKVTGSPSPRMGHTITVVGNDIYVVGGRSGPSEILNDIWVLERSNNRWSKVDCSGDFFRPRHRHAAAAVDRKVYVFGGLSDDGLCSCMNIMDTASIQWNVISPDDKWPCARHSHSLVSYGSKLFLFGGHDGQRALNDFYSFDTTTLKWNKENTNGKAPSPRFSHCMFIYKDYLGILGGCPIRESSQEIALLNLKHKIWFYVSIPSLSQCLCVRSSSVIIDDDLVIVGGGASCYAFGTRFSQPIKIDLHLLESIFKLAYNKEKEMSVQHGSVSNVDLLEGHEENCNPSDNVKVVIDTATLGSSPLVLQLEKKYAKLAKDILKKFGWLDLTRKVRVSQDNIHVLFPVSKTFHALITDKHLKVQPDDSCVFEELLPFSENKLFGASISLQKALEILLLCRGSILKDEVAISRKASKTPQTIMRELVSVLLDKKGLPSQLLEQLPTRWETLGDIIVLPKTCFKDPLWESVRDDLWPLVAKSLGAQRLARQGKITPNGTRDSTLELLVGNDGWLTHHENGICYSLDATKCMFSSGNRSEKLRMGKLDCRDEVVVDLFAGIGYFVLPFLVKANAKLVYACEWNPHALEALQRNVMDNHVADRCIILEGDNRLTAPKGIADRVCLGLLPSSECSWDTAVRALRAEGGMLHIHGNVNDSDESLWLDNVVKSITNIAKTHGLSWNVTVEHVERVKWYGPHIRHLVVDVKCRAT