Protein
Probable cleavage and polyadenylation specificity factor subunit 1
Organism
Oryza sativa subsp. japonica
Function
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
Similarity
Belongs to the CPSF1 family.
Sequence
MSYAAYKMMHWPTGVDHCAAGFVTHSPSDAAAFFTAATVGPGPEGDIDSAAAASRPRRLGPSPNLVVAAANVLEVYAVRAETAAEDGGGGTQPSSSSGAVLDGISGARLELVCYYRLHGNIESMTVLSDGAENRRATIALAFKDAKITCLEFDDAIHGLRTSSMHCFEGPEWQHLKRGRESFAWGPVIKADPLGRCGAALAYGLQMIILKAAQVGHSLVGEDEPTCALSSTAVCIESSYLIDLRALDMNHVKDFAFVHGYIEPVLVILHEQEPTWAGRILSKHHTCMISAFSISMTLKQHPVIWSAANLPHDAYQLLAVPPPISGVLVICANSIHYHSQSTSCSLDLNNFSSHPDGSPEISKSNFQVELDAAKATWLSNDIVMFSTKAGEMLLLTVVYDGRVVQRLDLMKSKASVLSSAVTSIGNSFFFLGSRLGDSLLVQFSYCASKSVLQDLTNERSADIEGDLPFSKRLKRIPSDVLQDVTSVEELSFQNIIAPNSLESAQKISYIVRDALINVGPLKDFSYGLRANADPNAMGNAKQSNYELVCCSGHGKNGSLSVLQQSIRPDLITEVELPSCRGIWTVYYKSYRGQMAEDNEYHAYLIISLENRTMVLETGDDLGEVTETVDYFVQASTIAAGNLFGRRRVIQVYGKGARVLDGSFMTQELNFTTHASESSSSEALGVACASIADPYVLLKMVDGSVQLLIGDYCTCTLSVNAPSIFISSSERIAACTLYRDRGPEPWLTKTRSDAWLSTGIAEAIDGNGTSSHDQSDIYCIICYESGKLEIFEVPSFRCVFSVENFISGEALLVDKFSQLIYEDSTKERYDCTKASLKKEAGDSIRIVELAMHRWSGQFSRPFLFGLLNDGTLLCYHAFSYEASESNVKRVPLSPQGSADHHNASDSRLRNLRFHRVSIDITSREDIPTLGRPRITTFNNVGGYEGLFLSGTRPAWVMVCRQRLRVHPQLCDGPIEAFTVLHNVNCSHGFIYVTSQGFLKICQLPSAYNYDSYWPVQKVPLHGTPHQVTYYAEQSLYPLIVSVPVVRPLNQVLSSMADQESVHHMDNDVTSTDALHKTYTVDEFEVRILELEKPGGHWETKSTIPMQLFENALTVRIVTLHNTTTKENETLLAIGTAYVLGEDVAARGRVLLFSFTKSENSQNLVTEVYSKESKGAVSAVASLQGHLLIASGPKITLNKWTGAELTAVAFYDAPLHVVSLNIVKNFVLFGDIHKSIYFLSWKEQGSQLSLLAKDFGSLDCFATEFLIDGSTLSLVASDSDKNVQIFYYAPKMVESWKGQKLLSRAEFHVGAHITKFLRLQMLPTQGLSSEKTNRFALLFGNLDGGIGCIAPIDELTFRRLQSLQRKLVDAVPHVCGLNPRSFRQFHSNGKGHRPGPDNIIDFELLCSYEMLSLDEQLDVAQQIGTTRSQILSNFSDISLGTSFL