OTOP3

Proton channel OTOP3

596 amino acids

Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.

Belongs to the otopetrin family.

66.296 kDa

MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA

Otop3

Proton channel OTOP3

577 amino acids

Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.

Belongs to the otopetrin family.

64.743 kDa

MASQTSAPAEPAPMPSPEAKTTEGASSYDQADMETKHAGSPCPPKQKSWLARHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVSVTLGDVWILLAALKVLSLLWLLYYTVGTTRKPHAVLYRDPHAGPIWVRGSLVLFGSCTVCLNIFRMGYDVSHIHCKSEVELIFPAIEIVFMIIQTWVLWRHCKDCVQVQTNFTRCGLMLTLATNLLMWVLAVTNDSMHREIEAELDALMEKFSGNGTNTCMCLNTTVCEVFRKGYLMLYPFSTEYCLICCAVLFVMWKNVSRSLAAHTGAHPNRSPFRLHGTIFGPLLGLLALVAGVCVFVLFQIEASGPDIARQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTLKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVATQPHELLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPAVSGVMEKQDVELPRRGSLRELGQDLRRASRAYIHSFSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVYLGA