ORF48

Alkaline nuclease

551 amino acids

Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules. Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate. Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides. Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.

Belongs to the herpesviridae alkaline nuclease family.

61.271 kDa

MARSGLDRIDISPQPAKKIARVGGLQHPFVKTDINTINVEHHFIDTLQKTSPNMDCRGMTAGIFIRLSHMYKILTTLESPNDVTYTTPGSTNALFFKTSTQPQEPRPEELASKLTQDDIKRILLTIESETRGQGDNAIWTLLRRNLITASTLKWSVSGPVIPPQWFYHHNTTDTYGDAAAMAFGKTNEPAARAIVEALFIDPADIRTPDHLTPEATTKFFNFDMLNTKSPSLLVGTPRIGTYECGLLIDVRTGLIGASLDVLVCDRDPLTGTLNPHPAETDISFFEIKCRAKYLFDPDDKNNPLGRTYTTLINRPTMANLRDFLYTIKNPCVSFFGPSANPSTREALITDHVEWKRLGFKGGRALTELDAHHLGLNRTISSRVWVFNDPDIQKGTITTIAWATGDTALQIPVFANPRHANFKQIAVQTYVLSGYFPALKLRPFLVTFIGRVRRPHEVGVPLRVDTQAAAIYEYNWPTIPPHCAVPVIAVLTPIEVDVPRVTQILKDTGNNAITSALRSLRWDNLHPAVEEESVDCANGTTSLLRATEKPLL

ORF48

Alkaline nuclease

551 amino acids

Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules. Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate. Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides. Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.

Belongs to the herpesviridae alkaline nuclease family.

61.252 kDa

MARSGLDRIDISPQPAKKIARVGGLQHPFVKTDINTINVEHHFIDTLQKTSPNMDCRGMTAGIFIRLSHMYKILTTLESPNDVTYTTPGSTNALFFKTSTQPQEPHPEELASKLTQDDIKRILLTIESETRGQGDNAIWTLLRRNLITASTLKWSVSGPVIPPQWFYHHNTTDTYGDAAAMAFGKTNEPAARAIVEALFIDPADIRTPDHLTPEATTKFFNFDMLNTKSPSLLVGTPRIGTYECGLLIDVRTGLIGASLDVLVCDRDPLTGTLNPHPAETDISFFEIKCRAKYLFDPDDKNNPLGRTYTTLINRPTMANLRDFLYTIKNPCVSFFGPSANPSTREALITDHVEWKRLGFKGGRALTELDAHHLGLNRTISSRVWVFNDPDIQKGTITTIAWATGDTALQIPVFANPRHANFKQIAVQTYVLSGYFPALKLRPFLVTFIGRVRRPHEVGVPLRVDTQAAAIYEYNWPTIPPHCAVPVIAVLTPIEVDVPRVTKILKDTGNNAITSALRSLRWDNLHPAVEEESVDCANGTTSLLRATEKPLL

ORF48

Tegument protein ORF48

402 amino acids

44.559 kDa

MEVCIPIPGIGDENCESWRAQIVAFGTTSGFVKTERILRGLFPERGHPGFLASLVVLKHTLASPGGLNTRLNLLPVLQMLKYVGQEMYMRAKCQATASDMTLIWDDCKDRFMLILEQACGCHQCMTVVEEITHCSAISAPPSSLSHGRHILSAGLINFARRQVLLGGSVSFSEFSIPDLIQTPEQYPFVDVEFRRELSLISSCLNVCWLYHIFIEHITSDVRRLESCMASVLEEYGGLSPTRPWAEAVTFLSQLPRPTRKPWKELSVSRINVEARLLDTLVMQLEKPVPVEIIKHALAILGTAGHVWNPEHQLACPDTRTCRERVSKGPCVGDGDVTLVHTARMDISNPSSVSPDGDVHYSGPPRTPAYGVVLECADDSDDSLDDFLENLSQTCDSSDDEYD

ORF48

Uncharacterized protein ORF48

278 amino acids

31.179 kDa

MNNGWDVSDSDEEPEMARPVSNKTELMRWMTDDFSFESILDTPAEQPRAISPEPVTPKKPKQPKKRPALKQPTLPFAAPAKRGMDWVAGLRANLPRIIDGLDVAIAIESDSHIPAWVHGSWVPALKCLMGDSMALAFWNKISNACSMGDIFWWLAHPAPHLKCIFATPTEWTTEEIKLIVGAVQKTAGGSMTSLESRERVLENVGVLFTAIYFQIGKFKCMGGWDDFWKRFQKACADSGLGIHMCFCGKSYAKRKNTHFLPQLNALNIYAIDQLPIIW

ORF48

Uncharacterized protein ORF48

160 amino acids

18.044 kDa

MYNTIMAGNTSIVCNNELVWETEIITNIILLKQEKISLESHKKKLDEQRRFGNTGHLILVTRLTDETINIIKAAEDEYYLLRGAISVEGVDSAFLRQPGVRASLNQLMDTLSLINDHLAITQQSSLPSDELKATVREIAVITENVKRIIILLSLLIMNIK

ORF48

Uncharacterized 7.1 kDa protein

63 amino acids

7.146 kDa

MNAQYATCYLCDELVYLFKKQFARTSASAAALYRKRMAIVRRGVVLCQRCSSALHGGDDPDRR

ORF48

Uncharacterized protein ORF48

48 amino acids

5.593 kDa

MRVVTFKAEEELLALLDRYAMNKGLYRSEVIREAIIEFLSVRGYKVNG

ORF48

Uncharacterized protein ORF48

48 amino acids

5.641 kDa

MRKAIVCFTIDANEKSLLSQLAERENKSLSQYVREIVLDRMIEELNEN