ORF20

Putative capsid protein V20

595 amino acids

May self assemble to form an icosahedral capsid. Most abundant protein in the virion.

65.381 kDa

MSNSAIPLNVVAVQEPRLELNNERTWVVVKGGQQVTYYPFPSTSFSSNQFNFICNPPSAQTVLDRLVFIQVPYDITFTANPSHAGITENLLQPGRDAFRAFPISSITNTLNATINGFPVNIELAQIIHALSRYHTPLKVKNGWMSMQPSFEDNYQSYRDADGANNNPLGVFTSAAGLSELPRGSYTMNVVTNTTTTARITGVLYEQVFLPPFLWDGEQAGGLANLTSLTFNWVLNNNLARIWSHSDITNDVSGNSTIGSMNISFQQPSMYLGFVTPRLNIPIPPRITYPYFKLSRYTTQFQNTLAPNASSTFKSNVVQLDSIPRKLYLFVKQSDNVIYQNLNNQITTPDVFLQINNLNLTWNNQQGILSGASSQNLYDFSVQNGYNKTWSEFNGVTQQFNGVSGQPTKVIGLEGGIVCLELGKDVGLRDDEAEGVIGNFNLQVQMTVTNTNQYVTVTPDMYIVAVYDGTLVISNTSAMASIGVASKEEVLNARITHGVSYNELQRIYGGDFFSSFKNFLGKVGNVAGKVNNFLKDSKIASSVLGAIPHPYAQVPGQILKNVGYGESHVGGGKKKGGVLIGGRQLTKAELRKELKM

ORF20

Ribonucleoside-diphosphate reductase small chain

579 amino acids

Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).

Belongs to the ribonucleoside diphosphate reductase small chain family.

66.994 kDa

MSQSTIKFDLGELTTTQCARLLSKFIRKATLTPEQFEILNTSYDELTEFDDHPLYGGATDHHKDIVGKYDHALLKPAVYQQLRDFATKMESSSWQQTEIDAESDIPTWEQISENERDCVRKVLAFFAVGDTLVKDRIAIFADEFPLPECKDFIDWQTVNEGVHQRVYNNYLDALVKDKIYLADLVNAYKDPEFAPIKKKVDWLGKIISVENDSRGEMVVGQVCTEAIMFAASFAILLKFRAPYMRALVLGNEFIRRDETLHFRFYAELLRLMPDRPSDERIAELLTEATEIELEFAEYVVPEGVKYITKDRLIQHVKANTNQVCEMLDINPIYFDQKGNVLLSPLLYMNTLESEQKINFFEGKATEYNTKQYKVDFNNLFPPVKKMIEFADEEEFIAAIVEGEGLSKDRNKDIVKQQLCLAWDHLSSHDMEGLVDMTWTLKDVHRIAMNHVIFNNGEFSNGYKFTVIDSGKVMYPTYETVEILESAVQGLIDDYNRDFSALDKGVEKFDKDKIRVAARFILDLLYIHPFSDGNGRTARLIMAHLIGKMTTPINREEYLKSIYHYRQTGDVSVFVDQFYR

ORF20

Putative matrix metalloproteinase

474 amino acids

Belongs to the peptidase M10A family.

53.655 kDa

MIIYFAVITCSLKLCRSYYKMLLNVSHTIQCVFSRMSWYTLAVILSTLVTIHASQGPEKFTLATAIVLKRGEDITWSVSRENLKYNYRTVVDTTSKAFAVWHTAGLNFRFVYNYSEAMIRISFKRRFHGEIGYDFDGLGSLLAHAYLPNQGDLSSEIHLDNDEIFSFSMKDSDYEGDNAPTSYFWTVLHEIGHSLGVQHSASPSSIMYGWYKSRSFGNGTIVLPKDDANAIHQLYFSNTKQYAAIPKFEKNKVVTTTPVPPADRSESTTNTTITTCFSFDSLSEIKHDATKDSISAYCAGVYDAISYVRGDLYVFVGDLHWRFDTSGMLHNGYPQPTGATWRLPSGSQVNSVFEWMQYIVIQTGKRYNLFVGTDFVRSVNFKVAPSITFASNNRVYAAFLGKLKDITGHLLRRKNLRWRYLPPIQLLQNELRAATDILVASNGMYIFKSGVHGVVVNGVVEHYKLNKGVWSNCR

ORF20

Uncharacterized 43.4 kDa protein

382 amino acids

43.394 kDa

MYQILIVLFLFALLYIVVWPFYQAFYHINHAQQDYNMTLTDRMDYIEAVMRRRQYVPMEALPVVRFDTNLGTLAGETLRCMSVPLYVSEIDLPMFDCGEVCEDPNAVYFFVGEGDTYVVNGHKLAVGGYCTTNSVPRDCNRETSVVLMSLNQWTCIAEDPRYFAGTGNMTQLAGRQHFDRILPGQSGRNVLFDRLLGREVNVATNTFRRSWDELLEDGSRRFEMRCNARDNNNNLMFVNPRNPLECLPNVCTDVNYVHSTVRPVFESGECDCGDEAVTRVRHVVPGDRTSMCASIVDGFDTNTASHRFRVECVNTHTPIDRFSSDKLLCPSDTFDSNTDAAFAFEVPGSYPLSGNGLDEPTHRVFLDTRSRVQYNDVRGALT

ORF20

Protein UL24 homolog

257 amino acids

May participate in nuclear egress of viral particles. Plays a role in the dispersal of several host nucleolar proteins including NCL/nucleolin and NPM1. Since deletion of host NCL/nucleolin negatively impact on nuclear egress, UL24 supposedly acts on this process through its effect on host nucleoli (By similarity). Induces cell cycle arrest in host cells at the G2/M phase following by apoptosis. The mechanism involves the inhibition of host mitotic complex cyclin-B/CDK1.

Belongs to the herpesviridae UL24 family.

28.413 kDa

MVRPTEAEVKKSLSRLPAARKRAGNRAHLATYRRLLKYSTLPDLWRFLSSRPQNPPLGHHRLFFEVTLGHRIADCVILVSGGHQPVCYVVELKTCLSHQLIPTNTVRTSQRAQGLCQLSDSIHYIAHSAPPGTEAWTITPLLIFKNQKTLKTVYSESPGAFPTPVHTTEGKLCAFLTARENADIRKVLSKVPKKPKMDRGGKILGPTPGKRAVYSQAHHGRNKKGRPWTAQPTRAKSRTKDKGTPAFPRAGPACSGP

ORF20

Uncharacterized protein ORF20

137 amino acids

15.476 kDa

MVSSKWNMITELFLGAANSYAQMRGKITHYEIQHDGTIQHEFIDPSNTEEKAWDLEDNPEQQISVKGYANSCTLTVKDDSNEVELVPSGRYKQYMENQILSQTMQTGSMDSQKMMYLSIANLATLLLFGIIGLSIIT

ORF20

Uncharacterized protein ORF20

102 amino acids

11.992 kDa

MASSDRFPLFCCVRNCIFRVSVDRVQPFIAHLRDHFGEKPGTSIRFRCPRCETILWRFPLGETVPDEMNIRRAWNHVALIQNECRSPETQIMCIHFLVDPES