ORF16

DNA polymerase processivity factor

408 amino acids

Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).

Belongs to the herpesviridae DNA polymerase processivity factor family.

46.09 kDa

MDLRSRTDDALDMELHAGFDAPEIARAVLTEKTLTGLISSISPLVNRLRDSILIFSDEGLIIHCSLETEQLYIPIPANMFDQYNWTGPRMVVLAATEGRSSLIDAFRHTKDPSTPTRLYFKFTGQPPERSIIQTMVWQRPGDCGPDDQVQCYKQVVKRELACYTMMFPNLTPDISICLKRDQFTRLQRLLKTFGFTTCFILTATDMYIQTAGGGFISFNVSLDINGSKPTPYNLIRSITNSKRILNNVVYGSGSMREFGVLLETHSGFRSAVQNLKLTRDETCYINFYLALTNSPMVGLYIQRSAPVHSFFYATFLSPKDLKEKLTSMQLFANMESVKDEPPLKKRRNLLTKRNEKNTGNKMGGKLPETTWQEGIGIREYCVAPPVDPAGTLDYSELSRESDVICTVK

ORF16

DNA polymerase processivity factor

408 amino acids

Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).

Belongs to the herpesviridae DNA polymerase processivity factor family.

46.06 kDa

MDLRSRTDDALDMELHAGFDAPEIARAVLTEKTLTGLISSISPLVNRLRDSILIFSDEGLIIHCSLETEQLYIPIPANMFDQYNWTGPRMVVLAATEGRSSLIDAFRHTKDPSTPTRLYFKFTGQPPERSIIQTMVWQRPGDCGPDDQVQCYKQVVKRELACYTMMFPNLTPDISICLKRDQFTRLQRLLKTFGFTTCFILTATDMYIQTAGGGFISFNVSLDINGSKPTPYNLIRSITNSKRILNNVVYGSGSMREFGVLLETHSGFRSAVQNLKLTRDETCYINFYLALTNSPMVGLYIQRSAPVHSFFYATFLSPKDLKEKLTSMQLFANTESVKDEPPLKKRRNLLTKRNEKNTGNKMGGKLPETTWQEGIGIREYCVAPPVDPAGTLDYSELSRESDVICTVK

ORF16

Protein kinase ORF16

387 amino acids

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

42.939 kDa

MTSSGFLRAHPGVVRRCGFTRGGGLKVGPCALTDPGLAWVHAYYTDEALNWLAGLDNPLWKSGADVMDLLPGDMYVSEHVFKKILSRVGPEFFDSFIPIREVEECILFGFSPLSSTGMAALKAIDLVYGGYAPAAPGIPMEVYAWEMAYKIGAAPRLLRWVLIEGEGIEQFATLAESGLRGSLRDYIGTHPSGCKTPMDLGLVVKNVHGLVAALGMLMDSNIYHGDLKIDNLTVTEPGGPYKLIDFEFAHPFEARMRPMIEARGPITWLMPGTPACNPPEHDEETPCRDRRMKELGVTWQLGLIMLETIVLDEALVRDENMEWKRPDFKRLVSAVMEENGSLAPHDPRLLEGYLDLIGECLKRDTAVRMDLVTLMTELSLLIEKFKL

ORF16

Uncharacterized protein ORF16

308 amino acids

35.915 kDa

MNVEIGQSDSGKDYVLTGKDNKILSYQTPDLQYTTLGKFIIYRLLHDRDVKILITGKGKTTGTGKTTLAIVLAKWINEVRNEIFNLNEQWHAKDYSFMDVWEYLEKYREAKPGDPLITDELEYMADKRRHMTNENVKFSQAWSILRYKNAVTLGTAPGLSDLEKRVIETADIWINVVHVGKANTYYLTFDDFEWEPIYRRLRQGQFKESICWDELNDENYQWLKQEKENLGVPGLDDNGQENQLEQSDLNKREREVKNSTVKEMLKLLYENSLHDSITQSDIADVCGVSQQQVSNLKRELEKDNEIPT

ORF16

Uncharacterized protein V16

130 amino acids

15.477 kDa

MAQNNKQTKQEINEDVVPYDELYELLMVADKDNVHKDEIIITLNNEKKLTEEKYMVCRKSYEELAQDYRSIKHKMNVFAPKGSLYNNYVKPKLLGSLTEERKREINSNFEKQRLEIINKEHEALKKLRGD

ORF16

Uncharacterized protein ORF16

76 amino acids

8.985 kDa

MYSLLLHLTPRHISPNPDPALHYPMTRLFRQCCPMVWLSHLLLHGVVQHASETYYRIPWPALWSCFFALVFMTEDS