OPT1

Gene

OPT1

Protein

Oligopeptide transporter 1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

799 amino acids

Function

High affinity transporter for glutathione. Also transports tetra- and pentapeptides like the opioids leucine enkephalin (Tyr-Gly-Gly-Phe-Leu) and methionine enkephalin (Tyr-Gly-Gly_Phe-Met) across the cell membrane.

Similarity

Belongs to the oligopeptide OPT transporter family.

Mass

91.616 kDa

Sequence

MSTIYRESDSLESEPSPTPTTIPIQINMEEEKKDAFVKNIDEDVNNLTATTDEEDRDPESQKFDRHSIQEEGLVWKGDPTYLPNSPYPEVRSAVSIEDDPTIRLNHWRTWFLTTVFVVVFAGVNQFFSLRYPSLEINFLVAQVVCYPIGRILALLPDWKCSKVPFFDLNPGPFTKKEHAVVTIAVALTSSTAYAMYILNAQGSFYNMKLNVGYQFLLVWTSQMIGYGAAGLTRRWVVNPASSIWPQTLISVSLFDSLHSRKVEKTVANGWTMPRYRFFLIVLIGSFIWYWVPGFLFTGLSYFNVILWGSKTRHNFIANTIFGTQSGLGALPITFDYTQVSQAMSGSVFATPFYVSANTYASVLIFFVIVLPCLYFTNTWYAKYMPVISGSTYDNTQNKYNVTKILNEDYSINLEKYKEYSPVFVPFSYLLSYALNFAAVIAVFVHCILYHGKDIVAKFKDRKNGGTDIHMRIYSKNYKDCPDWWYLLLQIVMIGLGFVAVCCFDTKFPAWAFVIAILISLVNFIPQGILEAMTNQHVGLNIITELICGYMLPLRPMANLLFKLYGFIVMRQGLNLSRDLKLAMYMKVSPRLIFAVQIYATIISGMVNVGVQEWMMHNIDGLCTTDQPNGFTCANGRTVFNASIIWSLPKYLFSSGRIYNPLMWFFLIGLLFPLAVYAVQWKFPKFKFAKHIHTPVFFTGPGNIPPSTPYNYSLFFAMSFCLNLIRKRWRAWFNKYNFVMGAGVEAGVAISVVIIFLCVQYPGGKLSWWGNNVWKRTYDNDYKKFYTLKKGETFGYDKWW

Protein

Oligopeptide transporter 1: OPT1

Gene

OPT1

Protein

Oligopeptide transporter 1

Organism

Arabidopsis thaliana

Length

755 amino acids

Function

Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner.

Similarity

Belongs to the oligopeptide OPT transporter (TC 2.A.67.1) family.

Mass

85.349 kDa

Sequence

MTSVFDEHKPSDDSHESKIVINGEEEVLEEENDNPIEEVRLTVPITDDPTLPVLTFRTWTLGLFSCILLAFVNQFFGFRSNQLWVSSVAAQIVTLPLGKLMAKTLPTKKFGFPGTNWSWSFNPGPFNMKEHVLITIFANTGAGGVYATSIITIVKAFYNRQLNVAAAMLLTQTTQLLGYGWAGIFRKFLVDSPYMWWPSNLVQVSLFRALHEKEDLQKGQQTRFRFFIIVFCVSFAYYIIPGYLFPSISAISFVCWIWKSSVTAQIVGSGLKGLGIGSFGLDWSTVAGFLGSPLAVPFFAIANFFGGFFIFLYIVLPIFYWTNAYDAQKFPFYTSHTFDQTGHTYNITRILNEKNFDINLDAYNGYSKLYLSVMFALLYGLSFGSLCATISHVALYDGKFIWGMWKKAKTATKDKYGDVHSRLMKKNYQSVPQWWFIAVLVISFAFALYACEGFDKQLQLPWWGLILACAIALFFTLPIGVIQATTNQQMGLNVITELIIGYLYPGKPLANVAFKTYGYISMSQALYFVGDFKLGHYMKIPPRSMFIVQLVATVVASTVCFGTTWWLITSVENICNVDLLPVGSPWTCPGDEVFYNASIIWGVIGPGRMFTKEGIYPGMNWFFLIGLLAPVPFWYLSKKFPEKKWLKQIHVPLIFSAVSAMPQAKAVHYWSWAIVGVVFNYYIFRRFKTWWARHNYILSAALDAGTAIMGVLIFFAFQNNDISLPDWWGLENSDHCPLAHCPLAKGVVVEGCPVF

Protein

Oligopeptide transporter 1: OPT1