Protein
Probable scoulerine-9-O-methyltransferase OMT3B
Organism
Papaver somniferum
Function
Methyltransferase involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (By similarity). Catalyzes the conversion of (S)-scoulerine to (S)-tetrahydrocolumbamine (By similarity).
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Sequence
MEVVSKIDQENQAKIWKQIFGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPAQPVNEDRLYRILHFLVHMKLFNKDATTQKYSLAPPAKYLLKGWEKSMVPSILSVTDKDFTAPWNHLGDGLTGNCNAFEKALGKGIRVYMRENPEKDQLFNEGMACDTRLFASALVNECKSIFSDGINTLAGVGRGTGTAVKAISKAFPDIKCTIHDLPEITSKNSKISRDVFKSVPSADAIFMKSILHEWNDEECIQILKRCKEAIPKGGKVIIADVVIDMDSTHPYSKSRLAMDLAMMLHTGGKERTEEDWKKLIDAAGFASCKITKLSALQSVIEAYPH