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OCLN

Gene
Ocln
Protein
Occludin
Organism
Rattus norvegicus
Length
523 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. May be involved in the organization of actin in endothelial cells.
Similarity
Belongs to the ELL/occludin family.
Mass
59.186 kDa
Sequence
MSVRPFESPPPYRPDEFKPNHYAPSNDMYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLVIVMCIAVFACVASTLAWDRAYGTGIFGGSMNYPYGSGFGSYGGGFGGYGYGYGYGYGGYTDPRAAKGFLLAMAAFCFIASLVIFVTSVIRSGMSRTRRYYLIVIIVSAILGIMVFIATIVYIMGVNPTAQASGSMYGSQIYTICSQFYTPGGTGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIVFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDMPPPPSDYAERVDSPMAYSSNGKVNGKRSYPDSLYKSPPLVPEVAQEIPLTLSVDDFRQPRYSSNDNLETPSKRTPTKGKAGKAKRTDPDHYETDYTTGGESCDELEEDWLREYPPITSDQQRQLYKRNFDAGLQEYKSLLAELDEVNKELSRLDRELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNYCKQLKSKLSHIKRMVGDYDRRKT
Protein
Occludin: Ocln

Gene
OCLN
Protein
Occludin
Organism
Homo sapiens
Length
522 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.
Similarity
Belongs to the ELL/occludin family.
Mass
59.144 kDa
Sequence
MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGYGYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
Protein
Occludin: OCLN

Gene
OCLN
Protein
Occludin
Organism
Pongo abelii
Length
522 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Similarity
Belongs to the ELL/occludin family.
Mass
59.234 kDa
Sequence
MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFTCVASTLAWDRGYGTSLLGGSIGYPYGGSGFGSYGSGYGYSYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPVDDFRQPRYSSSGNFETPSKRAPAKGRAAKSKRTEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
Protein
Occludin: OCLN

Gene
OCLN
Protein
Occludin
Organism
Canis lupus familiaris
Length
521 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1.
Similarity
Belongs to the ELL/occludin family.
Mass
59.275 kDa
Sequence
MSSRPFESPPPYRPDEFKPNHYAPSNDVYGGDMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLVIVMCIAIFGCVASTLAWDRGYGTGLMGGSIGYPYGSGFGSYGTGYGYGFGYGYGYGGYTDPRAAKGFLLAMVAFCFIAALVIFVTSVIRSDISRTRRYYLTVIILSAFLGVMMFIATIVYIMGVNPTAQASGSLYSSQIYAMCNQFYASTATGLYMDQYLYHYCVVDPQEAIAIVLGFMVIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDMPPPPSDYVERVDSPMAYSSNGKVNDKRLYPESSYKSTPVPEVVQELPATSPADDFRQPRYSSSGHLEPPSKRAPSKGRTGRPKRLEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQAELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSPDYKNKRNYCKQLKSKLSHIKKMVGDYDRQKT
Protein
Occludin: OCLN

Gene
Ocln
Protein
Occludin
Organism
Mus musculus
Length
521 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Similarity
Belongs to the ELL/occludin family.
Mass
59 kDa
Sequence
MSVRPFESPPPYRPDEFKPNHYAPSNDMYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTGLFGGSLNYPYSGFGYGGGYGGGYGGYGYGYGGYTDPRAAKGFLLAMAAFCFIASLVIFVTSVIRSGMSRTRRYYLIVIIVSAILGIMVFIATIVYIMGVNPTAQASGSMYGSQIYMICNQFYTPGGTGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDMPPPPSDYAERVDSPMAYSSNGKVNGKRSYPESFYKSTPLVPEVAQEIPLTLSVDDFRQPRYSSNGNLETPSKRAPTKGKAGKGKRTDPDHYETDYTTGGESCEELEEDWVREYPPITSDQQRQLYKRNFDAGLQEYKSLQAELDDVNKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKRNYCKQLKSKLSHIKRMVGDYDRRKP
Protein
Occludin: Ocln

Gene
OCLN
Protein
Occludin
Organism
Gallus gallus
Length
504 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1.
Similarity
Belongs to the ELL/occludin family.
Mass
55.864 kDa
Sequence
MFSKKSYDGPPAGYGPPTGYGAPTADYGYGSPPPGSYYVDDAPQLFYKWTSPPGAVRGLQAGVLVLCIAIFACVASTLAWDYGYGLGGAYGTGLGGFYGSNYYGSGLSYSYGYGGYYGGVNQRTANGFMIAMAVLCFLAQLGLLVAALSKSGATRSRRFYLAVLVLSAVLAFVMLIASIVYIMGVNPQAQMSSGYYYSPLLAMCSQAYGSTYLNQYIYHYCTVDPQEAVAAVCGFLIVILLCLICFFAQKTRSKIWRYGKANIYWDRAPVVQEGPDVEEWVKNVADGASVQDETATLAYSEKPTSPVAAPPYSYVPPPSAGYYPSGTYSSRGDQPDRALSASPVHGEEEEEKGKDQPSRPPARRGRRRRRNPELDESQYETDYTTAVESSDERDQEQWASLYPPITSDGARQRYKQEFDTDLKRYKQLCAEMDSINDRLNQLSRRLDSITEDSPQYQDVAEEYNQLKDLKRSPDYQSKKQESKVLRNKLFHIKRMVSAYDKVRG
Protein
Occludin: OCLN

Gene
ocln
Protein
Occludin
Organism
Xenopus laevis
Length
493 amino acids
Function
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Similarity
Belongs to the ELL/occludin family.
Mass
55.112 kDa
Sequence
MYSRPSNYAPSKDVYGGEMRSQPAYSYYPEEEIQHFYRWSSPPGIIKIMSILIVVMCVGIFACVASTLPWDLDITGQSMGYGMGSGSYSGGYTGYGFGGSQMGLGFAYGGNYTDPRAAKGFILAMAAFCFIIGLVIFVMLVTRTPLSTSRKFYLIVIIVSAIIGGLVFIATIVYTVGVNPVAQASGSAFYTQIVSICNQFYSPVQTGVFVNQYLYHYCVVEPQEAIAIVLGFLIVVAFAIIIFFAVKTRKKINQYGKTNILWKKNHIYEDGDPQVEQWVKNVAENSAPALSDYNEKVDGSVADYRSANGVQAYPSQNNISHPIAEEELPLKEDYGMSPRHYSSSSDATTKKAPPKKRPGKPRRSDLDTNEGGYNTGGESADELEDDSWDSEYPPITQTKQRQEYKQEFASDLHEYKRLQAELDELSKIPVPSLNRELGQSSRKDSEEYRTVADKYNRLKEIKSSADYRNKKKRCKGLKTKLNHIKQMVSNYDK
Protein
Occludin: ocln

Gene
OCLN
Protein
Occludin
Organism
Potorous tridactylus
Length
489 amino acids
Function
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Similarity
Belongs to the ELL/occludin family.
Mass
54.076 kDa
Sequence
MMYEKRSYTGYGHPSSHYDYPPPSGPPGSFYLADVPPQHFYQWRSPPGIVRILQGSVVILCLVIFACVASTLAWEYYGSGGLLGYGGGLGSYYNGYYGGYNGYYYGGLTNPRAANGFMIAMAVLCFLVTLGLVIAGLSKASGARSRRFYLLVAVLSGLLAFVMLIASIVYVVGVNPRAGLGASSGSLYYNQMLMLCNQMMSPVAGGIMNQYLYHYCMVDPQEAVAIVCGFLTVILLCVICYFAQKTRHKIWKYGKPNIFWDKPLATAEGPNVEEWVKNVSGDVGTQDETATLAYSEKPISPLTSAFLPAQENGYGHSTPSSPSVPPPEGPSPPEEKDKGSVSRPPARRGHRQRPRPTGLEESQYETDYTTAAESSGEQNRDDWASLYPPIISDAIRQTYKAEFNNDLQRYKALCAEMDDIGTQLRQLSHELDCLPEGSLRYQGVAEEYNRLKDLKRSPEYQSKKLETQSLRDKLCHIKRMVGGYDQSRS
Protein
Occludin: OCLN