Protein
4-hydroxy-2-oxovalerate aldolase 2
Organism
Nocardioides sp. (strain ATCC BAA-499 / JS614)
Function
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
Similarity
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Sequence
MNETRTTVFVQDVTLRDGMHAIRHQLAPGEVAQIAAALDVAGVDAIEISHGDGLAGSSLNYGPGSHTDWEWIEAAAANIQRARLTTLLLPGIGTVDELRKAHDLGVRSVRVATHCTEADVSAQHIETARDLGMDVAGFLMMSHMAAASELAAQAALMESYGAHCVYVTDSGGRLTMDAVRDRVRAYRDVLDATTEIGIHAHENLSLSVANSVVAVEAGVTRVDASLAGQGAGAGNCPIEAFVAVANILGWQHGCDLYQLQDAAEDLVRPLQDRPVRVDRETLTLGYAGVYSSFLRHAEKAAQTYDLDVRTILTEVGNRRLVGGQEDMIVDIAMELSEVAADR