Protein
L-lysine 4-hydroxylase
Organism
Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10)
Function
Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (4R)-4-hydroxy-L-lysine.
Similarity
Belongs to the clavaminate synthase family.
Sequence
METIIESRQRINSPGVLPPPLSPLIVDVTPKERASISNVANILLKAFGHYEHPDFISALHLNAFQLLPERIAGILSRFGTDFSRHQYGALVFRGLTEVDQEALGPTPPSWKETDYSKLVKYGFICSLLHGAIPSKPVQYYAQRKGGGLLHAVIPDEKMSHTQTGSGSRTDLFVHTEDAFLFNQADFLSFLFLRNEEQVPSTLYSIRSHGDTNAIMAELFKPIYKCPKDANYADDENAGEEVTTSILYGNRERPFIRFDAAEQIYNEKAGQTPEAMHNLVRFWDEAKQLIYNDFVPDSGDLIFVNNHLCAHGRNSFVAGYRNENGQLVKCERRLMLRMMSKTSLINIQSVTQLNDPYFIMEEHYGKLFHSQQ