NTR2

Gene

NTR2

Protein

Thioredoxin reductase 2

Organism

Arabidopsis thaliana

Length

383 amino acids

Function

Possesses thioredoxin-disulfide reductase activity towards thioredoxins O1, O2 and F3.

Similarity

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

Mass

40.635 kDa

Sequence

MCWISMSQSRFIIKSLFSTAGGFLLGSALSNPPSLATAFSSSSSSSSAAAAVDMETHKTKVCIVGSGPAAHTAAIYASRAELKPLLFEGWMANDIAPGGQLTTTTDVENFPGFPEGILGIDIVEKFRKQSERFGTTIFTETVNKVDFSSKPFKLFTDSRTVLADSVIISTGAVAKRLSFTGSGEGNGGFWNRGISACAVCDGAAPIFRNKPLVVIGGGDSAMEEANFLTKYGSKVYIIHRRDTFRASKIMQQRALSNPKIEVIWNSAVVEAYGDENGRVLGGLKVKNVVTGDVSDLKVSGLFFAIGHEPATKFLDGQLELDEDGYVVTKPGTTKTSVVGVFAAGDVQDKKYRQAITAAGTGCMAALDAEHYLQEIGSQEGKSD

Protein

Thioredoxin reductase 2: NTR2

Gene

NTR2

Protein

Pre-mRNA-splicing factor NTR2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

322 amino acids

Function

Involved in pre-mRNA splicing and spliceosome disassembly. Promotes release of excised lariat intron from the spliceosome by acting as a receptor for PRP43. This targeting of PRP43 leads to disassembly of the spliceosome with the separation of the U2, U5, U6 snRNPs and the NTC complex.

Mass

36.647 kDa

Sequence

MAIKKRNKIRLPSGSPEEVGIDGSAHKPMQQIKPLVSNDSEDDDNDICVLQPIKFKKVPKRDITFDGEQAIKEDNSHYEDLYHSKKNTNASTRNKDDLLILNMEDLMEGNHHLLSDSSEAGSSSEGEHISSIPTRGEIAKLKAQKSLSRRKISESDVTTERDYVKLLDSEDKREIMETIRLNGGLKRNNEKEITNFSDDEMQGFQDEMLALTDNQIAIQKDSKRKIIEKAINEVPYRTNEEWETQLLSKGNINKSNEKIITPLPVLFPDDDESGNSIERINEMVSKICLQRKKVEMRLQALEKTKIDLEKSKASLINKLIGN

Protein

Pre-mRNA-splicing factor NTR2: NTR2