Protein
Nonribosomal peptide synthetase 5
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Function
Nonribosomal peptide synthesis (NRPS) is a key mechanism responsible for the biosynthesis of bioactive metabolites which are potentially contributing to organismal virulence.
Similarity
Belongs to the NRP synthase family.
Sequence
MNLTLTTTSITIQPSATMANRAPTLLDHFHDQLQKHSSSVAIEDGTQSADQGAWERVTYAQLDALSDSWSKRLRQAGVGAGCIVPLLSKRSVAMVAATLAILKLRAAYVSIDIDSWGKDRIDTVLKTVNPQIIVSTSPCPKDHYPYPVVALERNDFDETVTSNGTQWTRNDEDSIDRGNDLAYIIFTSGTTGIPKGVKIGQRSISRYVKEGGDLPFNFNTTHGTRVLLICSIAFDVCAGVMFNTLCNGGTLVLADPSTFETAAKTCHVLPLTPSILVTLDPKAGFDTVEKIFLGGESPSPSLIEAWSSPRRRLYNAYGPTETTCTAFMGELLPGSPITIGYPISYSTVTLLDEDGMESVEGEICIAGLGLALGYFHDPERTNSAFVEWNGVRIYKTGDYGRRTKHGLQFCGRRDSVVKNRGFLINLEADVEPALLSYDKVDSASAFMSQGQLIAFVTPTSAKEGLREYLANTVSSFLVPDTIYSLDEFPRTSNGKVDRRSLMRMHELEQGSDTASLERGLGAVESVRRGLSHVLRLPESQILPASSFRHLGGHSLAAVMLVSVLRRMGFGISVAEVLLLDTVENIAAAVVELSDIPHALSAQEDLIERLRHDISTTRPLDEGVTIAPMTDMQTRLLGASVATPGLSFIKTSFTLDHPEKEDLTSTLRAAWVRLHQTHEILRTAFVLTASNGTQIISQEPDFSWKEKFVTESEWESVCRREEHLDVADFPDFDAENRASLSRVVLIIAPRRRTRFVWTVHHSLIDGWSMATLMRDFASCLDGKPIPAPPQFAQVAQAIGQLKAESSDRAVSFWKEYLDGYTPAQRLRVSPPSDVSDYTQAALSRKLTVSVSALEDAARDRFAVTPATLLYAAWGLLLSRYSGTDRAALGAVLSGRSLPIPGVENIIGPLINTLPLAINTQEAQSTYSFVQSVFRRLCDILEFQWSPVALIQEGCGCNPSELFETLFALQYDFPQTPWKSSEVPEPRDIRYEEATQVPLTVLLDNANGQFEVRFIYRRSHFGDATVQRMIGQFGNLLENLIAAQPDTDLSNVTGQMFNNRVYEMSIAKPGQPVSACKVPESLTEAIENSIQAHPDIYAVEGLTGRLTYREFGRMTEHISQRLLQHIQPGSVACMISDGSLLWLLAMVAIIRAGAIYCPVDEKLPRDRKDYMVRNSRAALILYANSSQEPLCNGVPSLNMESIMQEISSSSGSPIATSRNRPSGDTVACLVYTSGSTGLPKAVQLQHKGILNVISQPEGRLYSRPGQRNAQMLSLGFDCCIKEVFSTICFGATLVLKDPENPISHLARVDATMATPSLLATLEPTDYPNLKVITVAGEAVSQVLNDKWAAGRTLINGYGPAECTLISTTAILHPGNRVSIGKPLPGLSCYLLDSNKRPVPMGVSGEIYISGVQVTPGYLHNEQETSKRFLSDSFNPGQVMYRTGDIGRMLEDGNIEYIGREDNQIKLRGFRIDLGEVQSTISKLASTASNVALIVSNGNLVAFMTPETIDVRSLAKSLETQLPQYAVPNRIIALATLPTSANNKVDSSALQRYLRDHGKDGAVVEDLETDTQRVLAVIWADMLGRDLNQTPISPSDRFFELGGHSLLQIKVAQAISKRWNIRPLPLKQVIRHHSLQDLSLAIDELVSDPRTVSTMPFLEMTPVARNGQLPLSYLEKEMLLNHLISGGSPAGNMNFVCKIRGDINAETLADAFQRVTADVEVFRTRYSVIEGTLFRQQAPGSVKVPRVVQTGNLSSFVHGRITKSFDLSTEPPVDVSIIIGTPMQAMLVVVMSHVVGDAATMATYLNRVSRTYDLLRSNSQTTNTSTVPDNLTYIDWAHWASTLQPNPRALTFWSSYLSNPPSPLTFGNPSPAPATYIGLTRSWTLPPSMYRKLSDLAAKASVTMHQLILAAVFFSLQCVDRRDDILVAAPFTHRTEPGTESLPGLFLDRLLLRIQRSPHQSSIFDFLSSVRETSQQALAHVIPFHTLRHSLAHKPSLIDPLFKVMVTYHTAADQRPLLDLSGAEVQPIPWRHTGGSKFPLKFEFTEMATQDLEVDMEYDLGCIREDIALRLEFALSFALQLMVLERETDDIIQLVQMSFCPGEGSPVGLTPSHEGSAELTNGTNKTDSTTGQQELENNLTDVVCECLGLEIQDVDADKSFWDLGAQSMDALKLQHLCEKRGVRVRLRDIFVSRSLLELATCAVII