NRK1

Gene

NRK1

Protein

Nicotinamide riboside kinase

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

241 amino acids

Function

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).

Similarity

Belongs to the uridine kinase family. NRK subfamily.

Mass

27.239 kDa

Sequence

MTSQLAGFKGTRGTLLVGIGGCSSSGKSTIAKLAVQVLEDAVLVHQDDFYRHDDEVPFDEEYQIGNWDVPEALDMAQFERELDHIRATGRPAAKLVHNGNIDDVGKFGISEEYLEELRRRYRGRISQPVVLVDGFMLYHDDKVAARFDCRLLVRAPYATMKARRASRGGYKTLDSFWQDPPFYFDKFVYKSYAATHARLFRNCDVEDRLVAPDVQEIYNGDEAQITCVLEQVLDAIAAAQC

Protein

Nicotinamide riboside kinase: NRK1

Gene

NRK1

Protein

Nicotinamide riboside kinase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

240 amino acids

Function

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).

Similarity

Belongs to the uridine kinase family. NRK subfamily.

Mass

27.69 kDa

Sequence

MTSKKVILVALSGCSSSGKTTIAKLTASLFTKATLIHEDDFYKHDNEVPVDAKYNIQNWDSPEALDFKLFGKELDVIKQTGKIATKLIHNNNVDDPFTKFHIDRQVWDELKAKYDSINDDKYEVVIVDGFMIFNNTGISKKFDLKILVRAPYEVLKKRRASRKGYQTLDSFWVDPPYYFDEFVYESYRANHAQLFVNGDVEGLLDPRKSKNIKEFINDDDTPIAKPLSWVCQEILKLCKD

Protein

Nicotinamide riboside kinase: NRK1

Gene

nrk1

Protein

Nicotinamide riboside kinase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

230 amino acids

Function

Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).

Similarity

Belongs to the uridine kinase family. NRK subfamily.

Mass

26.264 kDa

Sequence

MTRKTIIVGVSGASCSGKSTLCQLLHAIFEGSSLVHEDDFYKTDAEIPVKNGIADWDCQESLNLDAFLENLHYIRDHGVLPTHLRNRENKNVAPEALIEYADIIKEFKAPAIPTLEQHLVFVDGFMMYVNEDLINAFDIRLMLVTDFDTLKRRREARTGYITLEGFWQDPPHYFENYVWPGYVHGHSHLFVNGDVTGKLLDKRIQLSPSSKMSVRDNVQWAINSILNALQ

Protein

Nicotinamide riboside kinase: nrk1