NPH2

RNA helicase NPH-II

717 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

84.726 kDa

MDMQNITDLYKIDKKTTLYPNIINKYNYMAYLLFPNNATIFNSYITKKEVFEYPMQFAIALYPVYKLYWHNINICLNNRFIYLSNEFKNNISINTVYNLLYNNELKFEDDNIIINGKNLKISYSAYSYVTIISQITINISSLNKYQIYGIIESANYLGILSSYKQNKYFDKNLFSFTKSELRSTMIDVQLKIFEIFISKKNCIISGGTGIGKTTVIPKLFWWFNLLFDGYEFWNTSNENKNINDFIFKPNFEKNKTILSLPRKALIRQMGINYIKSLGFDNISGSPIILKYKDVKKEKEYYNNNPILYPFVLSVNRITINNIKHSNSVIIDEIHEHDKFGDIAIAIARTKKKKYNIRNIVLISATIESDIDNIRIYFKNIVEIYIPGVSLFPVKEIECEDKDVISILKNYMPSVGKSVIIFYETIKKINEYKEILESILIDKIYKIYTIHSKITNINAIINKLQNDKKHIHIILSTNYLESSITITNATLVIDNGKMYQKKFLTGSTMYITESMYIQRKGRVGRISKGTYIRTYSKDLLQTTFKHINYQYLWEYILVFKYNNMDYYNDLFIKPDDPSRIENTLNYLKNINIDIDKYISLLYSKFNKYEINMVEYLSIYINNSTSDIILLNEFIDNIRNSDKYIFPYRLTEIFHKLNVRCRCINITETEEGNINCSFVILNNYDGDPFFKLSFEKSNLICRYNKIYYIVSMSPLYLID

NPH2

RNA helicase NPH-II

684 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

76.557 kDa

MKNLPGVFAFPDNETIFAHAYSQRELEAMLPARAGAQPHAFAYAAWPLSKHRWRGAFVCRQRGVLKLNLELDAGAFERVPRSEAERFEPEQSDARALMHRGADGTVMSFECYSFLRCRPGLELREAGLALLRGLVVGGNRMRIFSGVRRAGASAATSAGMLGNESPFERAPFASLRIDAQAALFRAWAARRPTVVTGGTGVGKTSQVPKLLLWFNYLFGGTEDLDVLAPARERPVVLSLPRVALVRMNGHALRRALGFDALEGSPVELRYGDLAPADANSSRSPFRLVVSTNQLTLGALFAHGTVILDEVHEHDQMADIMLAVLRVHRARVDSIVLMSATLEDDRERLQEFFPDAEFVHIPGSTRFEIRGVYVRNSSDPRDARAYDEEERRNVSAALSAHRPRAGRCGILFVASVAQCEDYARLLTREHPELGVYVVHGKTPNVDALLAEVYASARPCVLVSTPYLESSVTIRTVTHVYDTGRVFVPAPFGGRQMLISPAMRTQRRGRVGRVMPGTYVYFYDPARLAPIKRIDSEFLYNYIIYARHYGLVLPDDLYVQPSDLELLRRCEEYLDGFGLAPERLFELASTRYLRMVEYAKIYARGGARAEELNRFERDGVVTEDVLASIRALNLRARVLSARARRGQFLHTCEVAFGPYAGTRFLLANRRRLRGDIFMVTERSFVL

NPH2

RNA helicase NPH-II

682 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

79.808 kDa

MTTNDLFSIYAFSNMYDIFPRKYSQKELEEYHRKNPLFFSYTIFPVIKHRWSKAYICFQNNVYMLNIELDTSKPYDRVPIQHLIDIRPISTDIKKEIYKISDKTFITFECYSYLKCKGYNSIYDITLDDKRGLLSAGNILSIFSSNKQMPEKSSIGILKNPKPFTVIKFKSLSLITQLQIFELLRKRKQIVVTGSTGIGKTSQLPKVIMWYNYLFGGWDNLDRVRFDYISRPIVLSLPRVALVKSNGINFLQSLGFSDFEGSPVELRYGGKTEHTTRQHDGIVLSTNKLTSYSLSNYNIIIVDEIHEHDRIADIIISVLRKNIDTIHSLVLMSATLEDDRDRLQEFLPDVEFYHIEGPVLYSIKEIYVKNKYSYDSKAYTEEEKKNISTTLNWCRPRNGMCGILFLASVSQCISYKKYLEKSNSDMDFIIIHGKIPDITEVLNAVQRPGRERPCILVSTPYLESSITIRTATHVYDTGRVYVPKPFGGDQLFISKSMMTQRKGRVGRVSKGIYVYFYDMCLLKPIKSIDHEFLYEYIVYAKKFKLSLPNDLLVIPSDKDMLKKSEEYIKSFNISFDRLFEIYVNYFVNMVEYVKIYNKGGKKAENLDMFERNDILTGETLKDIKNLQLLVKINTTTRRKKMYCYKGEILFGPYMNTVIRLSSKQLYRNYVYMLTERSFTLYR

NPH2

RNA helicase NPH-II

678 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

77.789 kDa

MENHLPNIFYFPNCVTAFPYRYTQKELDDMKPVDRERFKYAVFPLIKHRWCRAYVVRDNHTFKLNVETSKRLRRVAYPTLVPLVGVNAALREYVMEDGTKISFECYSYLICKRTTSLHDVDDSTIRGLVEGGNQLNIFTNSVGSVTNTVGIFGNPNPFAKVPLKSLHPSMQCKIFTSWARRVPVVLTGDTGVGKTSQVPKLLLWFNYLFGGFTDLSTLTFEVQEKPIVLSLPRVALVKLHSETLLTSLGFEEIHGSPVSLKFGNMQERFVNTRFSRYGIVFSTHKITLNTLFKYSTVILDEVHEHDQTGDIIIAVCRKYIRKLDSLFLMTATLEDDRRRIEEFFAESVFVHIPGGTLFSISEAYVKNSNDPLNRFMYIEEEKRNLANAIKTYTPPKQSSGIVFVSTVSQCEAYKQYLSERLPYKFYIIHGKVQNINDVLSDIYDNDGVSIIISTPYLESSVTVRNATHVYDTGRVYIPSPYGGCESFISKSMRDQRKGRVGRVNPGMYVYFYNVSELRPIKRIDFEFLHNYVLYAKVFDLQLPEDLFVKPTNVTRLHDVIEYIRSFDISDDVWTRLLSSYYIHILEYAKVYARGGSGALALDSFERTGNLTDDALDAIKSLNMRAKILSHKKASAHTYALRCKLLFGVYAGKVFTVYHKRPLTGYITMIAEHSFIPDY

NPH2

RNA helicase NPH-II

678 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

78.243 kDa

MENHLPNIFYFPNCVTTFPYRYTQKELDDMKPDERERFKYATFPIIKHRWSHAYVVKDNHVFKLNVETSKRLRRATPPTLSVPVSMNTMLREYITQDGTKISFECYSYLTCKKATSLHDLDDNAIRGLVEGGNRLQLFTNSVGSVKDTVGIFGNPNPFMKVPLKSLHPSMQCKIFESWIHHVPVVLTGDTGVGKTSQVPKLLLWFNYLFGGFVNLSTITFDVQEKPIVLSLPRVALVKLHSETLLTSLGFNEIHKSPVSLKFGNMQEQFVNTRFRRYGIVFSTHKITLNTLFNYSTVILDEVHEHDQTGDIIIAVCRKYIRKLDSLFLMTATLEDDRQRIEEFFTESVFVHIPGGTLFSISEAYVKNSNDSLNKFMYIEEEKRNLVNAIKTYTPPKQSSGIVFVSTVSQCDVYKQYLSERLPYKFYIIHGKIQNINDLLSDIYDNEGVSIIISTPYLESSVTVQNATHVYDTGRVYIPSPYGGREVFISKSMRDQRKGRVGRVKPGMYIYFYDVSELRPIKRIDFEFLHNYVLYSKVFDLQLPEDLFVKPTNMTRLRDVIEYIRSFNISDGVWTRLLSSYYIHILEYAKVYARGGQSAAALDSFERTGNLTDDALDAIKSLNMRAKIISHRKASTHTYALMCRLLFGVYAGKTFIAYHKRPLTGYITMITEHSFIPEY

NPH2

RNA helicase NPH-II

676 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

77.6 kDa

MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTAKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITDFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIRNVTHIYDMGRVFVPAPFGGSQEFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVQEAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN

NPH2

RNA helicase NPH-II

676 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

77.659 kDa

MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTTKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITDFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIRNVTHIYDMGRVFVPAPFGGSQEFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVREAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN

NPH2

RNA helicase NPH-II

676 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

77.572 kDa

MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTAKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITDFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIHNVTHIYDMGRVFVPAPFGGSQQFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVREAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYINIISDTIFVPVDNN

NPH2

RNA helicase NPH-II

676 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles.

Belongs to the DEAD box helicase family. DEAH subfamily.

77.6 kDa

MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTAKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITNFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIRNVTHIYDMGKVFVPAPFGGSQEFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVREAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN

NPH2

RNA helicase NPH-II

676 amino acids

NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity).

Belongs to the DEAD box helicase family. DEAH subfamily.

77.545 kDa

MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSNMERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEAHGKKVSPPSLGKPSHINLTAKQYIYSEHTISFECYSFLKCITNAEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITDFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLEIDKILEKVYSSPNVSIIISAPYLESSVTIHNVTHIYDMGRVFVPAPFGGSQQFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRINSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVQEAILSLNLRIKILNFKHKDNDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN