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NPFF

Gene
NPFF
Protein
Pro-FMRFamide-related neuropeptide FF
Organism
Bos taurus
Length
115 amino acids
Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. The neuropeptide FF potentiates and sensitizes ASIC3 cation channel.
Similarity
Belongs to the FARP (FMRFamide related peptide) family.
Mass
12.614 kDa
Sequence
MDARQAAALLLVLLLVTDWSHAEGPGGRDGGDQIFMEEDSGAHPAQDAQTPRSLLRSLLQAMQRPGRSPAFLFQPQRFGRNTRGSWSNKRLSPRAGEGLSSPFWSLAAPQRFGKK

Gene
Npff
Protein
Pro-FMRFamide-related neuropeptide FF
Organism
Mus musculus
Length
114 amino acids
Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Similarity
Belongs to the FARP (FMRFamide related peptide) family.
Mass
13.012 kDa
Sequence
MDSKWAALLLLLLLLLNWGHTEEAGSWGEDQVFAGEDKGPHPPQYAHIPDRIQTPGSLFRVLLQAMDTPRRSPAFLFQPQRFGRSAWGSWSKEQLNPQARQFWSLAAPQRFGKK

Gene
Npff
Protein
Pro-FMRFamide-related neuropeptide FF
Organism
Rattus norvegicus
Length
114 amino acids
Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF and SF potentiate and sensitize ASIC2 and ASIC3 channels.
Similarity
Belongs to the FARP (FMRFamide related peptide) family.
Mass
13.152 kDa
Sequence
MDSKWAAVLLLLLLLRNWGHAEEAGSWGEDQVFAEEDKGPHPSQYAHTPDRIQTPGSLMRVLLQAMERPRRNPAFLFQPQRFGRNAWGPWSKEQLSPQAREFWSLAAPQRFGKK

Gene
NPFF
Protein
Pro-FMRFamide-related neuropeptide FF
Organism
Homo sapiens
Length
113 amino acids
Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Similarity
Belongs to the FARP (FMRFamide related peptide) family.
Mass
12.44 kDa
Sequence
MDSRQAAALLVLLLLIDGGCAEGPGGQQEDQLSAEEDSEPLPPQDAQTSGSLLHYLLQAMERPGRSQAFLFQPQRFGRNTQGSWRNEWLSPRAGEGLNSQFWSLAAPQRFGKK