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NLRP2B

Gene
NLRP2B
Protein
NLR family pyrin domain-containing protein 2B
Organism
Homo sapiens
Length
45 amino acids
Function
May function as a negative regulator of NF-kappa-B by preventing RELA/p65 phosphorylation at 'Ser-536', thereby inhibiting its transcriptional activity. Through NF-kappa-B regulation may control cytokine release upon Toll-like receptors activation and therefore play a role in modulation of innate immunity. May also play a role in cell cycle progression and apoptotic process.
Mass
4.993 kDa
Sequence
MVSSAQLDFNLQALLGQLSQDDLCKFKSLIRTVSLGNELQKIPQT