Nlrc5

Protein NLRC5

1915 amino acids

Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.

Belongs to the NLRP family.

211.71 kDa

MDAESIRLNNENLWAWLVRLLSKNPEWLSAKLRSFLPTMDLDCSYEPSNPEVIHRQLNRLFAQGMATWKSFINDLCFELDVPLDMEIPLVSIWGPRDEFSKQLGAGEESCPGPQLYHGAKRPFQSYGSSPRRKNSKKQQLELAKKYLKLLKTSAQQWHGGVCPGAWLTPHSPQTYIPPVLQWSRATAPLDAQEGATLGDPEAADNIDVSIQDLFSFKAHKGPRVTVLLGKAGMGKTTLAYRLRWRWAQGQLDRFQALFLFEFRQLNMITQLPTLPQLLFDLYLMPESEPDAVFQYLKENAQEVLLIFDGLDEALHADSVGTDNAGSALTLFSELCHGNLLPGCWVMTTSRPGKLPSCVPTEAATVHMWGFDGLRVEKYVTCFFSDLLSQELALKEMRTNARLRGMCAIPALCTVTCFCLRRLLPGSSPGQSAALLPTITQLYLQMVETFSPSETLLDTSILGFGKVALRGLDTGKVVFSVEDISPQLMSFGAVHSLLTSFCIHTRPGHEEIGYAFVHLSLQEFFAALYLMASHTVDKDTLVEYVTLNSHWVLRTKGRLGLSDHLPAFLAGLASHTCHMFLCQLAQQDRAWVGSRQAAVIQVLRKLASRKLTGPKMIELYHCVAETQDLELARFTAQSLPSRLSFHNFPLTHADLAALANILEHRDDPIHLDFDGCPLEPHCPEALVGCGQVENLSFKSRKCGDAFAEALCRSLPTMGSLKTLGLTGSRITAQGISHLIQTLPLCSQLEEVSLHDNQLKDPEVLSLVELLPSLPKLQKLDLSRNSFSRSILLSLVKVAITCPTVRKLQVRELDLIFYLSPVTETATQQSGASDVQGKDSLKEGQSRSLQLRLQKCQLRIRDAEALVELFQKSPQLEEVNLSGNHLEDDGCRLVAEAASQLHIAQKLDLSDNGLSQTGVTYVLKAMSTCGTLEDLHISLLNNTVVLTFAQEPREQEGSCKGRAPLISFVSPVTSELSQRSRRIRLTHCGFLAKHTETLCEALRASCQTHNLDHLDLSDNSLGGKGVILLTELLPGLGPLKSLNLSRNGLSMDAVFSLVQCLSSLQWVFHLDVSLESDCIFLRGAGTSRDALEPKFQTGVQVLELSQRYTSRSFCLQECQLEPTSLTFLCATLEKSPGPLEVQLSCKSLSDDSLKILLQCLPQLPQLSLLQLRHTVLSSRSPFLLADIFNLCPRVRKVTLRSLCHAVLHFDSNEEQEGVCCGFPGCSLSQEHMETLCCALSKCNALSQLDLTDNLLGDIGLRCLLECLPQLPISGWLDLSHNNISQEGILYLLETLPSYPNIQEVSVSLSSEQIFRMCFSKKEGAGTSLRLCECSFSPEQVSKLASSLSQAQQLTELWLTKCHLDLPQLTMLLNLVNRPTGLLGLRLEEPWVDSVSLPALMEVCAQASGCLTELSISEIQRKLWLQLEFPHQEGNSDSMALRLAHCDLETEHSHLMIQLVETYARLQQLSLSQVSFNDNDGTSSKLLQNILLSSCELKSFRLTFSQVSTKSLTHLAFGLGHCHHLEELDFSNNSLREEDTELLMGALQGTCRLKKLHLSFLPLGASSLALLIQGLSRMTLLQDLCLSHNQIGDVGTQCLAAILPKLPELRKFDLSHNQIGDVGTQCLAAILPKLPELRKFNLSHNQIGHVGTQCLAAILPKLPELRKFDLSRNQIGDVGTQCLAAILPKLPELRKFDLSGNRIGPAGGVQLVKSLTHFEHLEEIKLGNNALGEPTALELAQRLPPQLRVLCLPSSHLGPEGALGLAQALEQCPHIEEVSLAENNLAGGVPRFSKRLPLLRQIDLEFCKIEDQAARHLAANLTLFPALEKLLLSGNLLGDEVAAELAQVLPQMGQLKKVNLEWNRITARGAQLLAQGLVQGSCVPVIRLWNNPILNDVAQSLQSQEPRLDFSITDQQTL

NLRC5

Protein NLRC5

1866 amino acids

Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.

Belongs to the NLRP family.

204.595 kDa

MDPVGLQLGNKNLWSCLVRLLTKDPEWLNAKMKFFLPNTDLDSRNETLDPEQRVILQLNKLHVQGSDTWQSFIHCVCMQLEVPLDLEVLLLSTFGYDDGFTSQLGAEGKSQPESQLHHGLKRPHQSCGSSPRRKQCKKQQLELAKKYLQLLRTSAQQRYRSQIPGSGQPHAFHQVYVPPILRRATASLDTPEGAIMGDVKVEDGADVSISDLFNTRVNKGPRVTVLLGKAGMGKTTLAHRLCQKWAEGHLNCFQALFLFEFRQLNLITRFLTPSELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDGLDEALQPMGPDGPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPAEAAMVHMLGFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDHAPGQSVALLPNMTQLYMQMVLALSPPGHLPTSSLLDLGEVALRGLETGKVIFYAKDIAPPLIAFGATHSLLTSFCVCTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTLHSRWVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTETTAELQRAPDLQESDGQRKGAQSRSLTLRLQKCQLQVHDAEALIALLQEGPHLEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSNNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLCKALGGSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVLGLVRCFSTLQWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRQRCIPRSLCLSECPLEPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLDCLPQLPQLSLLQLSQTGLSPKSPFLLANTLSLCPRVKKVDLRSLHHATLHFRSNEEEEGVCCGRFTGCSLSQEHVESLCWLLSKCKDLSQVDLSANLLGDSGLRCLLECLPQVPISGLLDLSHNSISQESALYLLETLPSCPRVREASVNLGSEQSFRIHFSREDQAGKTLRLSECSFRPEHVSRLATGLSKSLQLTELTLTQCCLGQKQLAILLSLVGRPAGLFSLRVQEPWADRARVLSLLEVCAQASGSVTEISISETQQQLCVQLEFPRQEENPEAVALRLAHCDLGAHHSLLVGQLMETCARLQQLSLSQVNLCEDDDASSLLLQSLLLSLSELKTFRLTSSCVSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRLDLSHLLLNSSTLALLTHRLSQMTCLQSLRLNRNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSISSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGALSLAQALDGSPHLEEISLAENNLAGGVLRFCMELPLLRQIDLVSCKIDNQTAKLLTSSFTSCPALEVILLSWNLLGDEAAAELAQVLPQMGRLKRVDLEKNQITALGAWLLAEGLAQGSSIQVIRLWNNPIPCDMAQHLKSQEPRLDFAFFDNQPQAPWGT

nlrc5

Protein NLRC5

1726 amino acids

Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms (By similarity).

Belongs to the NLRP family.

192.891 kDa

MKMEEMDLEEDVLDVVDQEASTIVDILCEQRDNVLQRIFALVDARTREQLQHLPNNRESISGLVDYFRTSDQHTCRRFLDIIWSFCENIPLELDIRIVNLAGSTAGALVNNSHVPDTENSPQSRYGKRARLDQVQSYTNAVKSFLQKKFEKVTKDIKKEVCLNNTWLCWRTQKYARVRDRPAKSQEGEEVSLEHKESVEALLMKTGRVVMLSGQAGSGKTLLMHCLAHHWAQGSYPSIELLFLLEFRQLNLISQPLSLKELLFRFFLPSDEDDEQSEAVLNYVLSNPEKICFIFDGYDEFGARFKDPKELECSVNPYQQLPLADLLSALCSAKILPGCTVLVTCRPRDVFDLFGSSDYFVAELLGFNQQRVKEYTQEYFQEKGCEIKERAVSLLMDSHHLLSMSHVPGLCHVCCVCLDHFLTSDMSQQPGTQLPTSLTQIYLHILSAFISRCHGCGSSDNHTPLLQRYRVQIAMLSKLAMDGLENSRIVFPANELTTELMNFGANAGILSRLDLTCGDGSRRLGCAFTHLTIQEFMAALHLMTNPDITESQLKKKLNLKSRWTAKTDPKTVFTDSLHLYMCGLAAEACTSNLVLLKGSENARAIVLKRQDAVLKTLQRFVVSGRQTGPKIIELCRCAHETQNIDLARAIGPRDRFELRNIRLNPVDIDALAFVISSANQMVCLDFGACYIEPECLNIIPNCKNLEELNFRSRKYDDKFAEALSGILPKLQSLKQLHFISGGLTNIGAAKLFKASECCPQITRLNVSDNYLTDESVKKITELFPKLAKLTSVILGKNNISINGIFILAGKMAAFPNIKEVYANAKKKEINVQFSANTTNSASTDDLNNTEESKQLILNDWNLKWTNVHNLCPMLRGCSSLTVLNLSHNALGNRGLKKLLEHLPTLDTIQEINVSDNGVDMDGVVLLSPLLCTLKDLTEVEASHNGKKMLVLTFSSSIIDALKQVTSEGCDILHKKLSLTHSDIHPTDMNKLCKNLIKCPNPLNLDFSHGTLKDESTEKLLKFLPNMASLNLLNLSHIQMSTDSALLLVQLLSDCQRTTTVELRQLGETFIKFLQDKSEAATCKFNQYRLSSANLAKLCEILEHCHHLTDLDLSSNFLKDEDVKTFVQFLPKLQISGSVSLNNNNLTEVGVLYLLSLMHTCERVAAVEVSLGKEEQQDIIGFVQKNCTGKTFRLSSCTVQSQNVLFLLNKLATLNSVQTLELRNNSFSADTIKYLITEFCGDCNHRTIRIMEPWIKGEAAVGLVQCCLELNPNIKEIRVEKTCLKLSVESLVSATIPNEWENGNCSLSAVHCISFDDCEVEGQHLSSLQSALRNCPSLQELHFSQLTMGADGAEFLSSVLPSLKNLKILSLSSKGETEDEAVIFALQHAQKHLEQLSLAHHVIKDRGAAVLGNALQGFTRMRSLSLLKCLDWTATGGRDLVRGLVQCHSLEEIRLDSIELDEESIDCFAQGLQAMTSLKKISLNKTISKEGSGVLCLLASLHPLIELEEIELIGLRMGDRGVEELVKHIPKWTRLRKINLSENRVSDHAGEMLVKALSHCRALQQIHLFRNNLGHSSAAVLGQVLPSLSELTELDLSENQMESKGCSSVCEALVSMKALKKLHLTSIGTSDLVNVASCLKHCTSIEDISLSWNNCENDVVLKLAEVLPQCSKLKRLDLEANNINTSGAMALATCLQFCPWIEVIRLWRNPIKKDDLILKDKRLNFSST