NKX2-3

Gene

NKX2-3

Protein

Homeobox protein Nkx-2.3

Organism

Homo sapiens

Length

364 amino acids

Function

Transcription factor.

Similarity

Belongs to the NK-2 homeobox family.

Mass

38.406 kDa

Sequence

MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAACAQGTLQGIRAW

Protein

Homeobox protein Nkx-2.3: NKX2-3

Gene

Nkx2-3

Protein

Homeobox protein Nkx-2.3

Organism

Mus musculus

Length

362 amino acids

Function

Transcriptional regulator essential for normal development and functions of the small intestine and spleen. Activates directly MADCAM1 expression. Required for homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. May have a role during pharyngeal organogenesis.

Similarity

Belongs to the NK-2 homeobox family.

Mass

38.09 kDa

Sequence

MMLPSPVTSTPFSVKDILNLEQQRHFHGAHLQAELEQHFHSAPCMLATAEGTQFSDAGEEDEEEEGEKLSYLNSLAAAEGHGDSGLCPQSYVHTVLRDACSGPKEQEEEVVSERSQKSCQLKKSLEAAGDCKTSEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGTASAATTAMQPACSATGGGSFVNVSNLGGFGSGGGAQPLHQGAAAGSACTQGTLQGIRAW

Protein

Homeobox protein Nkx-2.3: Nkx2-3