NKP2

Gene

NKP2

Protein

Inner kinetochore subunit NKP2

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

153 amino acids

Function

Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.

Similarity

Belongs to the NKP2 family.

Mass

17.862 kDa

Sequence

MNSEQLLHNYVSDSLLTTLISFQEFKQQLQSYTSDEQQLQHWYELLQARDARVTSELEARIKQFFITLRSRLLRFLESEQLSHSLSLETLIDALYKINDLLQQRLQILDDAIQEKTSELAEFENMVRSPSAGDNAIPGLLQIIQSYINLLEEN

Protein

Inner kinetochore subunit NKP2: NKP2

Gene

NKP2

Protein

Inner kinetochore subunit NKP2

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

151 amino acids

Function

Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis (By similarity). Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:29046335).

Similarity

Belongs to the NKP2 family.

Mass

17.658 kDa

Sequence

MLHEVLYKHLDGILVSRLYTEDQFVDLFSRTIPESNTVIASQLYKSYEENDQRIIEKIDKLIDNKLSLIRVELEREQIEDSISLEEVNKLLHSIDDMLQQHLNQLNIELDNKNTKLLKYAMELSDIEAIDTSMYDNVAKLITDMETNQPSS

Protein

Inner kinetochore subunit NKP2: NKP2