Protein
Inner kinetochore subunit NKP2
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Function
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis (By similarity). Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:29046335).
Similarity
Belongs to the NKP2 family.
Sequence
MLHEVLYKHLDGILVSRLYTEDQFVDLFSRTIPESNTVIASQLYKSYEENDQRIIEKIDKLIDNKLSLIRVELEREQIEDSISLEEVNKLLHSIDDMLQQHLNQLNIELDNKNTKLLKYAMELSDIEAIDTSMYDNVAKLITDMETNQPSS