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NGRN

Gene
Ngrn
Protein
Neugrin
Organism
Mus musculus
Length
293 amino acids
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Similarity
Belongs to the neugrin family.
Mass
32.447 kDa
Sequence
MALSLSLFLGGRVRTSLARCGFASQVMAGPGSVSCEPDPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLRQDQKVLKKAGFTREIGQLPVSEDTLKALSAGRSVSGLLMAGDEVSSKSQNHSTALKVAKSHPHSTDAQKKREGRDKRIQVLEESLVPATTALGHQRELQKSATSDSEATGRAGSDTLPSAVLLEELKPGEPGDQSFSSKVVQRGHDFFDSNGNFLYRI

Gene
Ngrn
Protein
Neugrin
Organism
Rattus norvegicus
Length
293 amino acids
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Similarity
Belongs to the neugrin family.
Mass
32.951 kDa
Sequence
MALSLSLFLGGRVRAAVARCGFASQGVAGPGSISREPDPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKVLKKAGITRVVWQLPVSEDTLKPLSAGHPMSGPLLMPGDEVSSNSQTHSRALKVKSNAPSAEAQKKREEKNKRIRVLAESLVPTTTALGHQRELQKYTTHDSEADRRANNHILPSVEKLEELEAGEPGDQNFSSKVVQKGREFFDSNGNFLYRI

Gene
NGRN
Protein
Neugrin
Organism
Homo sapiens
Length
291 amino acids
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Similarity
Belongs to the neugrin family.
Mass
32.408 kDa
Sequence
MAVTLSLLLGGRVCAAVTRCGFATRGVAGPGPIGREPDPDSDWEPEERELQEVESTLKRQKQAIRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKVLKKAGLAHSLQHLRGSGNTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIESDTHRTNTPRRRKGRNKEIQDLEESFVPVAAPLGHPRELQKYSSDSESPRGTGSGALPSGQKLEELKAEEPDNFSSKVVQRGREFFDSNGNFLYRI

Gene
NGRN
Protein
Neugrin
Organism
Pongo abelii
Length
291 amino acids
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Similarity
Belongs to the neugrin family.
Mass
32.588 kDa
Sequence
MAVTLSLLLSGRVCAAVARCGFATRGVADPGPIGREPDPDSDWEPEERELQEVKSTLKRQKKAIRFQKIRRQMEASGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKVLKKAGLAPLLQQLRGSGNTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIESDTHRTNTPRRWKGRNKEIQDLEESFVPVAAPLGHPRELQKYSSDSESPRRTGNGALPSDQKLEELKAEEPGNFSSKVVQRGREFFDSNGNFLYRI

Gene
NGRN
Protein
Neugrin
Organism
Bos taurus
Length
287 amino acids
Function
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Similarity
Belongs to the neugrin family.
Mass
31.741 kDa
Sequence
MAFSPNVLLGGRVCAAVARSGFATRRVTIPGSTSREPDPDFDWEPEERELQEVESALKRQKKAIRFQKIRRQMEASGAPPRTLTWEAMEQIRYLHREFSESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKVLKKIGLARSIPELPGPGDSSKPLSAGQSVSGSLLIPGDEASSRGHGHSTALKAIELNTQSTNITTRQTERNKGVQGLEEGKDFVPVAAGHPTSTCRGARGIDSDGLPSDKRLEELKAGEAGDQIFSKRVVQRGREFFDSNGNFLYRI