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NFYA

Gene
nfyA
Protein
Nuclear transcription factor Y subunit alpha
Organism
Dictyostelium discoideum
Length
517 amino acids
Function
Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
Similarity
Belongs to the NFYA/HAP2 subunit family.
Mass
57.279 kDa
Sequence
MNQINYLTSERNFLPPTDRDILNLGNNSSNSNNNSSSSNNNNNNNNNNNNNNNNNNNNSNSNSNSNNNNNNNSNNNNSSSSPDHMSLHSNGMDIHHNQQNHHYQNIQHQPHHFQQNYDERRIDYGNNNNNNNTNSMNNSNNNSNNNSNNNSNNNNNNNNNNNNNNNNNNSNNNNNSNNNNFNYNIKQQPQQTLQNQIVNMNGNIITSNGNHHYPTPHMLYARMAEIVEEPLYVNAKQYNRILKRRAARAKLESENKLPKTRKAYQHESRHQHAIRRQRGCGGRFLTKADQAKLDAQNAANAAAAAANPNASSTSTTTSNITNNNNNNNNNNNTNNNNNNNNTNVNGSGGSGGSNKIASSDDDIENDVENDSDSANIKNNSNSPNQSSSSPPPSKSKVVKKSNTINKRNNNINNNNNNNNNNNNEKTQPISSSSSSSSPLLNNGHIQAQQNQSPSSSPSQNLPPLNFSNNINNNINNNGNPTNFNNNNPNNNPNNNNNNNPNNNSFLPPLSNFSNNRS

Gene
NFYA
Protein
Nuclear transcription factor Y subunit alpha
Organism
Homo sapiens
Length
347 amino acids
Function
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
Similarity
Belongs to the NFYA/HAP2 subunit family.
Mass
36.877 kDa
Sequence
MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Gene
Nfya
Protein
Nuclear transcription factor Y subunit alpha
Organism
Mus musculus
Length
346 amino acids
Function
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
Similarity
Belongs to the NFYA/HAP2 subunit family.
Mass
36.779 kDa
Sequence
MEQYTTNSNSSTEQIVVQAGQIQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Gene
NFYA
Protein
Nuclear transcription factor Y subunit alpha
Organism
Bos taurus
Length
341 amino acids
Function
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1 (By similarity).
Similarity
Belongs to the NFYA/HAP2 subunit family.
Mass
36.234 kDa
Sequence
MEQYAANSNSSAEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Gene
Nfya
Protein
Nuclear transcription factor Y subunit alpha
Organism
Rattus norvegicus
Length
341 amino acids
Function
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.
Similarity
Belongs to the NFYA/HAP2 subunit family.
Mass
36.294 kDa
Sequence
MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS