NFS1

Cysteine desulfurase, mitochondrial

497 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

54.467 kDa

MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDDNFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLEPLLSGGGQERGLRSGTLAPPLVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLSAEHTTLNGSPDHRYPGCVNVSFAYVEGESLLMALRDIALSSGSACTSASLEPSYVLHALGKDDALAHSSIRFGIGRFSTEEEVDYVVKAVSDRVKFLRELSPLWEMVQEGIDLNSIKWSGH

NFS1

Cysteine desulfurase, mitochondrial

490 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

54.436 kDa

MLRQVLRRSLSDSRRPLRSVGSISCSARASGIGMRAYSSQIFKEGMQLETHTDIQSAAREQAQERMGSEALASNNSVLKHAYQESVDHGTRPIYLDMQATTPTDPRVVDTMLKFYTGLYGNPHSNTHSYGWETSQEVEKARKNVADVIKADPKEIIFTSGATESNNMALKGVARFYKKRKNHIITTRTEHKCVLEAARSMKDEGFDVTFLNVNEDGLVSLEELEQAIRPETSLVSVMSVNNEIGVVQPIKEIGAICRRHKVFFHSDAAQAYGKIPIDVDEMNIDLLSISSHKIYGPKGIGALYVRRRPRVRMEPLLSGGGQERGFRSGTLPPPLVVGLGHAAKLMVEEYEYDSAHVRRLSDRLLKGLLSIEQTTLNGSADHRYPGCVNVSFAFVEGESLLMALRDIALSSGSACTSASLEPSYVLHAIGRDDALAHSSIRFGIGRFTTEAEVDYVIKAITERVEFLRELSPLWEMYKDGIDLNTIEWSGH

NFS1

Cysteine desulfurase, mitochondrial

488 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

53.489 kDa

MYKSIFKTTGRLGKTVSSRNFVTTLPKPLATSSSPATNAPNKTSNPKTGELHVSTPVDTAKISIEPPEGSSISLKSASRDASLFGTRPIYLDVQATTPVDPRVLDKMLEFYTGLYGNPHSSTHAYGWETDKEVEKARTYIADVINADPKEIIFTSGATETNNMAIKGVPRFYKKTKKHIITTQTEHKCVLDSARHMQDEGFEVTYLPVSSEGLINLDDLKKAIRKDTVLVSIMAVNNEIGVIQPLKEIGKICRENKVFFHTDAAQAYGKIPIDVNEMNIDLLSISSHKIYGPKGIGACYVRRRPRVRLDPIITGGGQERGLRSGTLAPPLVAGFGEAARLMKQESSFDKRHIEKLSSKLKNGLLSIPSTQFNGCNDAKSQYPGCVNVSFAYIEGESLLMALKDIALSSGSACTSASLEPSYVLHALGADDALAHSSIRFGIGRFTTEAEVDYVIQAINERVDFLRKMSPLWEMVQEGIDLNTIEWSGH

Nfs1

Cysteine desulfurase, mitochondrial

459 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor (By similarity).

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

50.57 kDa

MVGSVAGNMLLRAAWRRASLAATSLALGRSSVPTRGLRLRVVDHGPHSPVHSEAEAVLRPLYMDVQATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLVQNIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAEKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH

NFS1

Cysteine desulfurase, mitochondrial

457 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

50.196 kDa

MLLRAAWRRAAVAVTAAPGPKPAAPTRGLRLRVGDRAPQSAVPADTAAAPEVGPVLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWTQH

NFS1

Cysteine desulfurase, mitochondrial

457 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor (By similarity).

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

50.135 kDa

MLLRAAWRRAAVAVTAAPGPKPAAPTRGLRLRVGDHAPQSAVPADTAAAPEAGPVLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPEHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGVGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWTQH

Nfs1

Cysteine desulfurase, mitochondrial

451 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor (By similarity).

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

50.013 kDa

MLLRVAWRRASLAATSVALRRSSVPTRGLRLRVVDHAPHSAVPSEAEAVLRPLYMDVRATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKLYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLIQKIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVQKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH

nfs1

Probable cysteine desulfurase, mitochondrial

450 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (By similarity).

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

49.853 kDa

MNRSILKFVKNGIISSSSRINNNGFINKNNNNRWFATLPQPNRGIAGEKQPIYLDMQSTTPIDPRVLDAMLPLYTENYGNPHSKTHAYGWTSNDLVEDAREKVSKIIGADSKEIIFTSGATESGNIAIKGVARFYKEKKNHIITTVTEHKCILDSCRHLEMEGFKVTYLPVGENGLVDLELLKNTITPQTSLVTIMAVNNEIGVVQPIKEIGKICRENGVFFHTDAAQAVGKIPIDVNDMNIDLLSISGHKIYGPKGVGALFVRRRPRVRIEPITTGGGQERGIRSGTVPSTLAVGLGAACDIALKEMNHDAAWVKYLYDRLLKGITDNIPNVKVNGDLNARYYGNLNISFSYVEGESLLMAIKDVACSSGSACTSSSLEPSYVLRSLGVEEDMAHSSIRFGIGRFTTEQEIDYTIEILKKNVQRLRDMSPLWEMVQEGIDIKTIEWSQI

NFS1

Cysteine desulfurase, mitosomal

441 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters in mitosomes.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

48.744 kDa

MPLPNQIATSNVETKNFASLKRSDEPIAIAQASRTPAKIYFDFQATTPVDPRVLDAMLPYFTKKYGNPHSRTHSFGWESEKAVETARKQVADLIGAHEKEIIFTSGATESNNLAIKGAVDWKAQDGNPVHVITTQVEHKCVLDSMRFLEEKGARVTYMKVNKDGVIDLEELKRSISDDTVLVSIMGVNNEIGTVQPLEEIGKICKERNVLFHCDAAQMFGKLKIDVNKMNIDLLSISGHKIYGPKGVGALYVRRRPRVRLVPLFSGGGQERGLRSGTLPTPLIVGLGKAAAVCQEEMQRDLSWIESLSKKLYTCLKENIPNVIKNGSLQTNPLRWFPGCLNLSFPHVEGEGLLMALKNIALSSGSACTSASLEPSYVLRALGNDDELAHSSIRFGIGRFTTPCEIKEVAKQTTSAVKKLRDMSPLYEMEQEGIDLKTIKWT

NFS1

Cysteine desulfurase, mitosomal

432 amino acids

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters in mitosomes.

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

47.016 kDa

MIGGLKSCIEQPSLPKPSTLLPQDKACDTGGKRIFLDVQSTTPVDPRVLDAMLPFYTTVFGNPHSRTHRYGWQAEAAVEKARSQVASLIGCDPKEIIFTSGATESNNLALKGVSGFKLKEGKAAHIITLQTEHKCILDTCRNLEENGVEVTYLPVGNDGVVDIDDVKKSIKENTVLVSIGAVNSEIGTVQPLKEIGMLCKERGVLFHTDAAQGVGKIQIDVNEMNIDLLSMCAHKIYGPKGIGALYVRRRPRVRMVPLINGGGQERGLRSGTVASPLVVGFGKAAEICSKEMKRDFEHIKELSKKLKNMFKKNIEGVIINGSEKGFPGCVNVSFPFVEGESLLMHLKDIALSSGSACTSASLEPSYVLRALGRDDELAHSSIRFGIGRFTMAKEIDIVANKTVEAVQKLREMSPLYEMVKEGIDLSKISWTS