Protein
Mitochondrial glycine transporter
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Function
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Sequence
MSNNAAYAVTPVKTTSTSSRTTFHFAAGLCSGLTSSILLQPADLLKTRVQQSQKTASLLPTIKTILSSPHPIRGLWRGTLPSALRTGFGSALYFTSLNALRQGLAQTEASMAIAASSSDGKSRTSSSALPKLSNWGNLATGAVARTAAGFVMMPVTVLKVRYESDYYAYRSLYSAGRDIVRTEGVRGLFSGFGATAARDAPYAGLYVLFYEQLKRRLASVASSEQSEQPLKSTSSSSINFVSGGLAAGLATAITNPFDAVKTRLQLMPGKYGNMIRAVRLMIREDGVRSLFGGLGLRITRKALSSALAWTVYEELILRAEAHWAEKDKIDL