Protein
Adenylosuccinate synthetase
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MGITIVLGSQWGDEGKGKITDMLSQQATLCCRAAGGHNAGHTIVHENITYDFHILPSGLVSPSCVNLIGAGTVVHVPSFFKELASLEEKGLKDAGKRIFISDRAHVCFDLHSVVDGLEEAKLGGRKVGTTGKGIGPCYSDKAARRGVRIGEIMDEAVFERKLRSLHAGYTARFGELEYDVEEEIGRFKDYRKRLVPYVVDQLAFFKQYKDSPNTLVEGANALMLDLDHGTYPYVTSSSTGLGGAVQALSLNPTSITSVIGVVKAYTTRVGSGPFPSEQLNEYGDKLQSVGREFGVTTGRRRRCGWFDLVLCRYSQAINHYTALNLTKLDILDDFDEIKVAVAYVLPDGTRLTDTYPADADLLEKVKVEYVSLPGWKSNTMGVRKYEDLPANARAYIEYIERELGGVPVKWIGTGPARDHMICRE