Nell2

Protein kinase C-binding protein NELL2

819 amino acids

Required for neuron survival through the modulation of MAPK pathways (By similarity). Involved in the regulation of hypothalamic GNRH secretion and the control of puberty (By similarity).

91.432 kDa

MHAMESRVLLRTFCVILGLGAVWGLGVDPSLQIDVLTELELGESTDGVRQVPGLHNGTKAFLFQESPRSIKASTATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVHVLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTVKGTTYRESESWTDGCKNCTCLNGTIQCETLVCPAPDCPPKSAPAYVDGKCCKECKSTCQFQGRSYFEGERNTVYSSSGMCVLYECKDQTMKLVENIGCPPLDCPESHQIALSHSCCKVCKGYDFCSEKHTCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCTNDTICFNLDGGYDCRCPHGKNCTGDCVHEGKVKHTGQIWVLENDRCSVCSCQTGFVMCRRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWVQDCRQCRCLQGEVDCWPLACPEVECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHLCCSVDPQCLQEL

NELL2

Protein kinase C-binding protein NELL2

816 amino acids

91.27 kDa

MESRVLLRTFCLLFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSIKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHHPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTSFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWTDGCKNCTCLNGTIQCETLICPNPDCPLKSAPAYVDGKCCKECKSICQFQGRTYFEGQRNTVYSSSGVCVLYECKDQSMKLVESSGCPALDCAESHQITLSHSCCKVCKGYDFCSERHNCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECVTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCQDGCRNGGACIAANVCACPQGFTGHSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKIKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPEVECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL

NELL2

Protein kinase C-binding protein NELL2

816 amino acids

Required for neuron survival through the modulation of MAPK pathways (By similarity). Involved in the regulation of hypothalamic GNRH secretion and the control of puberty (By similarity).

91.346 kDa

MESRVLLRTFCLIFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSIKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL

NELL2

Protein kinase C-binding protein NELL2

816 amino acids

91.304 kDa

MESRVLLRTFCLIFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSVKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPLNSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL

Nell2

Protein kinase C-binding protein NELL2

816 amino acids

Required for neuron survival through the modulation of MAPK pathways (PubMed:12941464). Involved in the regulation of hypothalamic GNRH secretion and the control of puberty.

90.953 kDa

MESRVLLRTFCVILGLEAVWGLGVDPSLQIDVLSELELGESTAGVRQVPGLHNGTKAFLFQDSPRSIKAPIATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTMKGATYREFESWTDGCKNCTCLNGTIQCETLVCPAPDCPAKSAPAYVDGKCCKECKSTCQFQGRSYFEGERSTVFSASGMCVLYECKDQTMKLVENAGCPALDCPESHQIALSHSCCKVCKGYDFCSEKHTCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFLCICQTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCKNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCVHDGKVKHNGQIWVLENDRCSVCSCQTGFVMCQRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWAQDCRQCRCLQEEVDCWPLACPEVECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHVCCSVDPQCLQEL

nell2

Protein kinase C-binding protein NELL2

814 amino acids

91.052 kDa

MEFILGIFCVLFCLRAGAGFGVDPSLQIDIFEDLQLGEATPGVQQVQGFHNRSKAFLFQDTSRSIKASTENAERIFQKLRNKHEFTILVTLKQAMLNSGVILSIHHSDHRYLELESSGHRNEVRLHYRSGSHRSQTEVFPYILADDKWHRFSIAISASHLVLHIDCNKIYERIVEKTFMDVPPGTALWVGQRNNVHGYFKGIMQDLQIVVMPQGFISQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERSCTVKGNIYRELESWMDGCKKCTCTNGTAQCETLTCSAPNCLSGFSPAYVPGKCCKECQTVCVFQGQMYFEEEREAVYSSSGQCVLFQCKDNTMRRIESPECLPLNCPQSQHITLRNSCCKVCKGHDFCSEGHNCMGYSICKNLDDKAVCICRDGFRALREDNAYCEDIDECTEGRHYCRENTVCVNTPGSFMCVCQTGYLKIDDYSCTEHNECATNQHSCDENAMCFNTVGGHNCVCQPGYTGNGTDCRAFCKDGCRNGGTCIAPNICACPQGFTGPSCESDIDECTEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSLGGESCEDIDECATGRHSCSNDTVCFNLDGGFDCRCPHGKNCSGDCTHEGKIKHNGQIWVLENDRCSVCSCQVGLVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQSGELTYKSGDTWVQNCQQCRCLQGEVDCWPLPCPAIDCEFSVVPESECCPRCVSDPCQADIIRNDITKTCVDETNVVRFTGSSWIKHGTECTLCQCKNGHMCCSVDPQCLQEL

nell2

Protein kinase C-binding protein NELL2

814 amino acids

90.762 kDa

MEFILGIFCVIFCLRAGAGFGVDPSLQIDIFEDFQLGEATPGVQQVQGFHNRSKAFLFQDTSRSIKASAETAERIFTKLRNKHEFTILVTLKQAMLNSGVILSIHHADHRYLELESSGHRNEVRLHYRSGSHRSQTEVFPYILADDKWHRFSIAISASHLVLHIDCNKIYERIVEKTFMDVPPGTALWVGQRNNVHGYFKGIMQDLQIVVMPQGFISQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERSCTVKGNIYRELESWMDGCKKCTCTNGTAQCETLTCSVPNCLSGFAPAYVPGKCCKECQPVCMYQGQMYFEGEQEAVQSSSGACVLFQCKSNTMQRIESPECLPLNCPQSQHITLRSGCCKVCKGHDFCSEGHNCVEYSICKNLNDKAVCICRDGFRALREDSAYCEDIDECTEGRHYCRENTVCVNTPGSFMCVCQTGYLKIDDYSCTEHNECATNQHSCDENAVCYNTVGGHNCVCQPGYTGNGTVCKAFCTDGCRNGGTCIAPNICACPQGFTGPSCEADIDECTEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSLSGESCEDIDECATGRHSCSNDTVCFNLDGGFDCRCPHGKNCSGDCTHEGKIKHNGQIWVLENDRCSVCSCQVGLVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQSGELTYKSGDTWVQNCQQCRCLQGEVDCWPLPCPEIDCEFSVVPESECCPRCISDPCQADIIRNDITKTCVDETNVVRFTGSSWIKHGTECTLCQCKNGHMCCSVDPQCLQEL

nell2

Protein kinase C-binding protein NELL2

811 amino acids

89.142 kDa

MAFLQLFVGLLCGAAVSAFGVDPAVRIGVFQEFSPGQGFSGVTQVKGFRDDTRAFMFQGSSRSVRVPDAAAGHMLQKLRGKTEFSIALTLKQDKLNSGVILSIHHGEHRLLELESSGQKSEVRLHFRTGLQQTHTEIFPFTLADEQWHRVSVSISAAHLTLYVDCNRIYERVVPVPLMEIPEDSSFWVGQRNSAHGLFKGIMQDLQILVMPQGFITQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSSKLSLAEEKMSGLDSCYCERTCRVKDQIYREEQSWTDGCKNCTCSNGTVRCEKILCPPLDCPDGTTPAYVTGTCCKECQPMCLFSEQTLVEGQSCAVHHPSGLCQLFQCRDRTMHRVPGAEDCPALSCAESDQITLTDRCCRVCRGHDFCAEENICSENSDCVNLDAGASCGCKNGFRPLRLDSAYCEDIDECAEGRHYCRENTECVNTAGSFMCVCHTGFIRIDDYSCTEHDECASGQHDCDENALCFNTVGGHSCSCKPGYSGNGTVCRALCDGRCLNGGSCASPNVCVCVQGFSGQNCETDIDECSEGLVQCAAHATCVNLPGWYHCECRDGYHDNEVFSANGESCRDIDECRTGRSTCANDTVCFNLDGGFDCRCPHGHNCSGDCIHNSRVRHNAQIWVLDTDHCSVCSCQEGQVKCRRMVCDCENPTVDVLCCPECDPRLTSQCLHQNGLLTYSSGDTWIDSCQRCQCLQGEVDCWPLSCPPVDCDFTLVPEGECCPRCVSDPCQAHAVRSDISKTCIDEHGITRFSGSAWVKHGTHCTLCQCKNGHVCCSVDPMCL