NELF-B

Gene

NELF-B

Protein

Negative elongation factor B

Organism

Drosophila melanogaster

Length

594 amino acids

Function

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II.

Similarity

Belongs to the NELF-B family.

Mass

67.935 kDa

Sequence

MIMSTPAKNNNGTGLEDVNIPGQAYLREALTSCTDPLKAIESFQLENGVLLPSLRPMLPLLDLHGVRRLDFHTSLMEELRDKLIAHINEMGQKEPRERDKKLKELLVKSFPVVRVKSLRPVVMAILRNTQHIDDKYLKILVRDRELYADTDTEVKRQIWRDNQSLFGDEVSPLLSQYIREKEHILFDHTNLNNLFFHPTPKVRRQGEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMALHDLEVQEIISIDPCHKFTWCLDACIREKNVDIKRSRELQGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLINNEGMPRDNQILILLLRMLALGLSAWVMIDSQDFKEPKLDCQVVTKFLPALMSLMVDDQCRSLHAKLPPDERESALTTIEHSGPAPDAVEAYIQESSVASILAMYYTLHTARLKDRVGVLRVLAILSACKDDRAYEDPFLHSLIALLIPMSEEFATEDFCTTLFDEFIFAGLTRENVTSRHMLKLLWYVHNKLPAGRLATLMKAMQPTTAHNEHIHKLYEILQERIGTGAAETPVIEAPPMEFDSPLKSVPTPGPHYNVQ

Protein

Negative elongation factor B: NELF-B