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NCLN

Gene
NCLN
Protein
Nicalin
Organism
Homo sapiens
Length
563 amino acids
Function
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
Similarity
Belongs to the nicastrin family.
Mass
62.974 kDa
Sequence
MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAYVAVQHFSLLYKTVQRLLVKAKTQ
Protein
Nicalin: NCLN

Gene
Ncln
Protein
Nicalin
Organism
Mus musculus
Length
563 amino acids
Function
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
Similarity
Belongs to the nicastrin family.
Mass
62.908 kDa
Sequence
MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQGSASAAEVLLHTATANGFQMVTSGAQSQAVSDWLITSVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGRGSHLRLHVSKPPREGTLQHAFLRELETVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFTLSHLESHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQEEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ
Protein
Nicalin: Ncln

Gene
Ncln
Protein
Nicalin
Organism
Rattus norvegicus
Length
563 amino acids
Function
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
Similarity
Belongs to the nicastrin family.
Mass
62.992 kDa
Sequence
MLEEAGEVLENVLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTVDADVLSRRCVLMRLLDFSYEHYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETVVPVYFAVEDEALLSIYEQTQAASASQGSASAAEVLLHTATANGFQMVTSGAQSQAVSDWLITSVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGISVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDSLDHTDSSLLQDNVAFVLCLDTVGRGSHLRLHVSKPPREGTLQHVFLRELEMVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFTLSHLENHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQVQQEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLKDVRQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLALCIGAYLGMAYTAVQHFHVLYKTVQRLLLKAKAQ
Protein
Nicalin: Ncln

Gene
NCLN
Protein
Nicalin
Organism
Gallus gallus
Length
562 amino acids
Function
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
Similarity
Belongs to the nicastrin family.
Mass
62.423 kDa
Sequence
MLEEAGEVLESVLKASCLPLSFLLFVPAVLLLLGPPPAAEAAHESTVYRMQQYELGGQPYGTRSAVLNTEARTVEADVLSRRCVMMRLVDFSYEQYQKALRQSAGAVVIILPRSISSVPQDVVKQFMEIEPEMLAMETIVPVYFAVEDDELLSIYEQTRAASASQGSASAAEVLLHTATANGFQMVTSGAQSKAIHDWLIPSVEGRLTGLGGEDLPTVVIVAHYDSFGVAPWLSHGADSNGSGVSVLLELARLFSRLYTYRRTHAGYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTLGRGNSLHLHVSKPPKEGTLQHAFLRELEMVVASQFPEVKFSMVHKKINLAEDILAWEHERFAIRRLPAFTISHLESHRDSLRNSIMDRRSQVDTKALTQEYQDHCGGFDEGHLQPNREGSTCRSADLHGSDADPGGAARISDGLAEQSAQAAQLIDKDSTFLSTLEYYMGRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAIFDLLLAVCIAAYLGVAYVAVQNFGLLYRMIQRLSLKTKQQ
Protein
Nicalin: NCLN