Protein
Major facilitator superfamily multidrug transporter NAG4
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Function
MFS transporter involved in N-acetylglucosamine (GlcNAc) uptake (PubMed:19648376). Confers resistance to cycloheximide, 4-nitroquinoline-N-oxide, and 1,10-phenanthroline, and contributes to virulence (PubMed:12076781, PubMed:12589826).
Similarity
Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.
Sequence
MSHATDSTLDNASVDSEKVRDFGDDLQNHPVQPTRSILSKIRSRDDDARSLVSNNKGVERIISDLQEGAGQLGPLEQPYDIKKIETHPDPHTDYNEADPWKYPIDSESGLRLVEWVDGDKHNPKNISKAKKWLYTLVLGAVCFVVALGSAIVTGDMERPAEYFGVSEEVIILASVTVFVIGFGVGPLVFAPMSEEVGRKPIYVVTLFIAVVFIVPCGAAKNIATLIVCRLIDGIAFSAPMTLIGGSLADIWEGPERGTAMAIFSAAPFLGPVCGPIFGGLLCDHAPTWRWIYWTFLIVAGVFYAIFIAIVPETHHGILLKKRAKKLRKETGDSRYRSFNELQIRSFGEVAKTSLLRPFVLLSELIVFLMTIYMAICYGLLYMFFFAYPVVYQQGKGWSASLTGVMFIPIGVGVIIATIAAPFFNKDYNRRAQVYRDRGELPPPELRLIPMMIACWFVPVGLFAFAWSSYTWVSWAGPCFSGLAAGFGFCCLYNPANNYIVDSYQHYAASALAAKTFVRSIWGACVPLFTIQMYHRLGDQWATSLMAFISLACCAIPYLFFFFGARVRTFSRYAYTPETNTK