Protein
NADH-ubiquinone oxidoreductase 49 kDa subunit homolog
Organism
Trypanosoma brucei brucei
Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme.
Similarity
Belongs to the complex I 49 kDa subunit family.
Sequence
MLFLVVFLHLYRFTFGPQHPAAHGVLCCLLYFCGEFIVYIDCIIGYLHRGTEKLCEYKSVEQCLPYFDRLDYVSVCCNEHLLSLCFEYMLRCCLSLRCAFMRLLIVEFTRSFNGLLCISCMVLDLGCLSPLLWSFEERDKLMTFFDLCCGCRMHLAFMVLLGILDDFVFGFVDFLLLLIISCLFVMDCYDLLFVGNRLFYLRLRGLSFFDLYDLVFNSLSGVLSRSLGMVWDCRLFSCYELYFMFCYDYCFCFIGDAFDRLFLRLFDMRMSLLICKQCFFVGFFVFGFVCLFDYLYCDITIETIIMLFYSLWCCCLPGISFACVEHPKGEYCLLLCFCVGLCSRLRLRCADFLHICLLDVCLRGFLLHDLVAVLGNIDVVFGSVDR