Protein
Geranylgeranylglyceryl phosphate synthase
Organism
Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)
Function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
Sequence
MLRKRVEIGPVESGLWNAVETDGAAHLTLIDPASQDPERAVQMARSAADAGTTALMVGGSVGATGSALDRTVRAIKDSVDLPVILFPSSAAGLCDNADAVFFMSLLNSRSTSYLIENQALGAPIVSRYGIEAIPMGYIVVEPGGTVGWVGDAKLVPRRKPDIAAAYALAGRYLGMRLIYLEAGSGAESPVPTSMVSAVRDAIGDTLLVVGGGIRDAEAARKLVSAGADLIVTGTGVEESGDVFRFVKDIVTAIHV