Protein
Geranylgeranylglyceryl phosphate synthase
Organism
Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
Function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
Sequence
MRIKGKTAKYLQKLIDEGQPIHFSLIDPDKVKDIQSLSKVASSLFKAGTSAFLIGGTLGVSKEKLDSILSVLQDFSVPKIIFPSNINLISEKADAILFMSLLNSDDLYYVIGAQVSASIIVKTIGLEPIPTGYLIVGHGGTAAHIGRARVVPYDNPELAVAYALAAEYMGMEYLYLEAGSGAPDTVRPEMVKFVSKYSEINLIVGGGIRTPERAVELVKAGAKALVTGNVIETDIERAIKIIEAMQRVYRIE