Protein
Mas-related G-protein coupled receptor member A
Organism
Rattus norvegicus
Function
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Sequence
MDKTIPGSFNSRTLIPNLLIIISGLVGLIGNAMVFWLLGFRLARNAFSVYILNLALADFLFLLCHIIDSTLLLLKFSYPNIIFLPCFNTVMMVPYIAGLSMLSAISTERCLSVVCPIWYRCRRPKHTSTVMCSAIWVLSLLICILNRYFCGFLDTKYEKDNRCLASNFFTAACLIFLFVVLCLSSLALLVRLFCGAGRMKLTRLYATIMLTVLVFLLCGLPFGIHWFLLIWIKIDYGKFAYGLYLAALVLTAVNSCANPIIYFFVGSFRHQKHQTLKMVLQRALQDTPETAENTVEMSSSKVEP