Protein
Monocarboxylate transport permease protein
Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Function
Low-affinity transporter of alanine and high-affinity transporter of lactate and pyruvate. Can also transport other monocarboxylates such as propionate, butyrate, alpha-hydroxybutyrate or acetate. May be proton coupled. Required for optimal growth on alanine or pyruvate and ammonia.
Similarity
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Sequence
MTTDINGTALAVFIFFFVLVTVMGFVASRWRKPETLAHIDEWGLGGRNFGTWITWFLVGGDFYTAYTVIAVPALVYTVGAYGFFALPYTIVVYPFVFMVMPVLWKRAKDFGYVTAGDVVHGQYGSRGLELAVAATGVIATMPYIALQLVGMTAVLKALGLHGELPLAIAFIVLALYTYSAGLRAPALIAFVKDIMIYIVVIAAVALIPSKLGGYANVFASADAAFQAKGSGNLLLGGNQYVAYATLALGSALAAFMYPHTLTGIFASNSGKTIRKNAIMLPAYTLLLGLLALLGYMGHAANLKLDSANDVVPTLFKTLFSGWFSGFAFAAIAIGALVPAAVMSIGAANLFTRNFWKAYVDPDVSDAGEAKVAKITSLVVKVGALLVIIFLPTQFALDLQLLGGIWILQTLPALVFGLYTNWFRAPGLLAGWFVGFGGGTFLVWDAGWKPLHLISLGGEPFTVYTGLLALAANIAVAVVVNALLPAKAPVRA