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Mbar_A1251

Gene
Mbar_A1251
Protein
Protein archease
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
146 amino acids
Function
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
Similarity
Belongs to the archease family.
Mass
16.846 kDa
Sequence
MSSQGKQYEYLDHTADIKFQAYGKTREEVFENAALAMFNVIIDTKKISGDTAREIFLKSPDLESLLVDWLSELLYLFEVDEIVFREFRVDNIREENGEYSITAQALGEKYDLKSLPFETEIKAVTYNQLEITKTADGWKAQVVVDI