Protein
Ribonucleoside-diphosphate reductase large subunit
Organism
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)
Function
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Similarity
Belongs to the ribonucleoside diphosphate reductase large chain family.
Sequence
MENFFIVKKLASATYGKALNVDLNKLLQALNHHSLQGLISYCSALTILHYDYSTLAARLSVYLLHQSTASSFSKAVSLQAAQSCSRLSSHFVDVVYKYKAIFDSYIDYSRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRVAIMIHGMGRVVNMKMILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNVNDNLENLYDMVKTAGIISGGGGGIGLCLSGIRAKNSFISGSGLRSNGIQNYIVLQNASQCYANQGGLRPGAYAVYLELWHQDIFTFLQMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIHNRGDGTWYLFSPDQAPNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVVQVGNPYIGFKDAINRKSNLSHVGTITNSNLCIEITIPCWEGNEAEQGVCNLAAVNLAAFIRESSYDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSNMRHRPIGIGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELAKEKGSHPSFPGSAASKGLLQPDLWVRCGDLIPSWENRVAQTTQGVLTPKKWWQLRLAAIQGVRNGYLTALMPTATSSNSTGKNECFEPFTSNLYTRRTLSGEFIILNKYLMDDLEEINLWSEDIQQQLLNAGGSIQHILDIPAEIRERYKTSREMNQKILTKHAAARNPFVSQSMSLNYYFYEPELSQVLTVLVLGWKKGLTTGSYYCHFSPGAGTQKKIIRNSEKACNADCEACLL