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Mal-049

Gene
Mal-049
Protein
Uncharacterized protein F317L
Organism
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)
Length
318 amino acids
Similarity
Belongs to the asfivirus F317L family.
Mass
36.687 kDa
Sequence
MVETQMDKLGFLLNHIGKQITTKVLSNAHITQTMKEIILENNSVNVDGGAAKNVSKGKSPPKEKKHWTEFESWEQLSKSKRSFKEYWTERNEIVNTLLLNWDNVRAAIKKFLNDDREWCGRINMINGVPEIVEIIPSPYKAGENIYFGSEAMIPAEIYSRVANKPAMFVFHTHPNLGSCCGGMPSICDISTTLRYLLMGWTAGHLIISSNQVGMLTVDKRIIIDLWANENPRWLMAQKILDIFMMLTSRRSLVNPWTLRDLKKILQDYGIEYIIFPSNDFFIYEDVRLLMISKKWTNFFTLHELLNDLETIETKTSST

Gene
Mal-049
Protein
Apoptosis regulator Bcl-2 homolog
Organism
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)
Length
179 amino acids
Function
Suppresses apoptosis in host cell and thus facilitates production of progeny virions. Has the ability to potentially bind to all the members of the proapoptotic Bcl-2 family.
Similarity
Belongs to the Bcl-2 family.
Mass
21.068 kDa
Sequence
MEGEELIYHNIINEILVGYIKYYMNDISEHELSPYQQQIKKILTYYDECLNKQVTITFSLTNAQEIKTQFTGVVTELFKDLINWGRICGFIVFSARMAKYCKDANNHLESTVITTAYNFMKHNLLPWMISHGGQEEFLAFSLHSDIYSVIFNIKYFLSKFCNHMFLRSCVQLLRNCNLI