MX2

Interferon-induced GTP-binding protein Mx2

715 amino acids

Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

82.089 kDa

MSKAHKPWPYRRRSQFSSRKYLKKEMNSFQQQPPPFGTVPPQMMFPPNWQGAEKDAAFLAKDFNFLTLNNQPPPGNRSQPRAMGPENNLYSQYEQKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKQPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAEATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQKATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGEEVVRENETRLYNKIREDFKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPALSMLQKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAENMIQLQFRMEQMVFCQDQIYSVVLKKVREEIFNPLGTPSQNMKLNSHFPSNESSVSSFTEIGIHLNAYFLETSKRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQSETATKRRILKERIYRLTQARHALCQFSSKEIH

MX2

Interferon-induced GTP-binding protein Mx2

715 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity.

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

82.123 kDa

MSKAHKSWPHRRRNQFSSQRSLKKEMNFFQQQPPPFGTVPPQMTFPPNWQGVEKDPAFLTKDFNLLTLNNQPLPGNTSQPRAKGPENNLHNQYEQKVRPYIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKQPYKAWAGRISYQNTEIELQDPGQVEKEIHKAQNVMAGNGLGISHELISLEITSPEVPDLTIIDLPGIARVAVGNQPRDIGLQIKALIKRYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILTKPDLMDRGTEKSIINVVRNLTYPLKKGYMIVKCRGQQEIINRLSLAEATKKEITFFQTHPCFRVLLEEGSATVPRLAERLTAELITHIQKSLPLLEEQIRESHQKATEELRRCGADIPSQDADKMFFLIEKIKMFNQDIEKLIEGEEVVRENETRLYNKIREDFKNWIGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFETIVHQYIQHLVEPALSMLQKAVEIIRQAFVNMAKKHFGEFFNLNHTVQSKIEDIKVRHTEKAENMIQLQFRMEQIVFCQDQIYSVVVKKVREEIFNPLGKPSQNMKLNSHFPINESSVSSFNEIGVHLNAYFSETSTRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQSETATKRRMLKERIYRLTQARHALCQFSSKEIH

MX2

Interferon-induced GTP-binding protein Mx2

714 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity.

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

81.681 kDa

MSMSYRALKFRRHAPTSTQHHPKEDMNFHQQPPGLPGPALGQTMSPPPWQMGESNPDFLPNNFNQLNLDPQQPEADGGQQRSKGSENNLYRKYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIITRCPLVLKLTKRECEWTGKITYRNVTQQLHNPSEVEREIRRAQNIIAGNGVGISHELINLEVTSPEVPDLTLIDLPGITRVAVENQPQDIGLQIKALIKTYIQRQETINLVVVPCNVDIATTEALSMAQEVDPDGDRTIGILTKPDLVDKGTEKGVLKVMQNLTYHLKKGYMIVKCRGQQDITNKLSLAEATRKEVMFFQTHPYFRVLLDEGKATVPLLAERLTTELIWHINKSLPLLENQIKEKHQRATEELQQYGDDIPSNEGDKMFFLIEKIKLFNEDIEKLIEGEEIVIETESRLCNRIREEFTRWVLILTTNIEKVKSILNEEVSKYETKYRGKELLGFVNYKTFETVVKHYLGQLIDPALKMLQKAMEIIWQTFKDTAKKHFAEFCNLHQTVQNKIEDIKTKQMAEAANLIQLQFRMEKLVFCQDQIYGVVLNKVREEIFNSVGKASENPQSKHPFLNNQSSVSSIVEIGVHLNAYFTETSKRLANQIPFIIQYFMLQENGDKVQKAMMQLLQETQHYSWLLQEQSDTATKRKFLKEKIFRLTQAQQALYEFPHFKSI

MX2

Interferon-induced GTP-binding protein Mx2

711 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

81.442 kDa

MSKAHGSRPYRRHNVVIPRQQPEKEMNFVQQQPPPSDAAARQMMYPPNCQVGVQDPVYLAKEFNLLTLNPQQLEGSRHQQMAKGPEKSLYSQYEQKVRPCIDLVDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKRDPHKAWRGRISYRKTELQFQDPSQVEKEIRQAQNIIAGQGLGISHELISLEITSPEVPDLTLIDLPGITRVAVGNQPQDIGVQIKALIKNYIQKQETINLVVVPCNVDIATTEALSMAQEVDPNGDRTIGVLTKPDLVDRGTEKTVVNVAQNLTYHLQKGYMIVRCRGQEEITNQLSLAEATEKERMFFQTHPYFRALLEEGKATVPCLAERLTKELILHINKSLPLLEKQIRESHQRATDELHQCGDSIPSNEADKMFFLIEKIKLFNQDIDKLIEGEEIVKKNETRLYNKIREEFEHWALVLTANTQKVKNIVSEEVSVYEKQYRGKELLGFVNYKTFETIVHQYIEQLVEPALTMLRKTIEIVWQAFTDTAKKHFSVFSNLSQTIQNKIEDIKTRQAETAENLIRLQFRMEQLVYCQDQIYSVVLRKVRKEVFNPAGKAAQDLQLKFPFPKDLPSMSSNDEIGVHLNAYFLETSKRLANQIPFIIQYFVLQENGSCLQKAMMQILQEREQYSWLLQEHADTSAKRRFLKEKIYRLAQARRALYMFFS

MX2

Interferon-induced GTP-binding protein Mx2

711 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against influenza virus A (FLUAV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

80.327 kDa

MPKPRMSWPYQRHRQASSPPHPHKEMNFFPQQPLPLGAGPGQMTFPLNWQMGGKDLTKGLNMLTLSPQQPGGKSGQQTSKGPENNLYSPFEEKVRPCIDLIDSLRALGVEQDLALPTIAVIGDQSSGKSSVLEALSGVPLPRGSGIITRCPLALRLKKKECPWQGRISYRKVELQLQDPSQVEREIRKAQDAIAGSGVGISHELISLEVTSPEVPDLTLIDLPGITRVAVGNQPQDIGLQIKALIRKYIQEQQTINLVVVPCNVDIATTEALRMAQEVDPEGDRTIGILTKPDLVDTGAEKVVLNVMQNLTYHLKKGYMIVKCRGQQEILNKLSLAEATKREIAFFHSHPHFRILLEEGKATVPRLAERLTVELIGHISKSLPLLFSQIKEIHQSATEELRLCGASVPSNDADKMFFLIEKIKVFNQDIENLAEGEEIVKEKEARLYNKIREEFKSWIVTLDCNSKKVKNIIHEEVSKYDRQYRGKELMGFVSYKTFESIVRQYLEELVDPALGMLQTVVEIVRQTFSDTAQKNFGEFSNLNQTTQNKVDSIAARAAERAEGLIRLQFRMEQLVFCQDDIYRVDLKAVREELFNPVAEHPQSLQLRLPFVNGPSPVSSITEIGVHVNAYFMGTSQRLANQIPFIIQYCVLQESRDHLQKAMMQMLQGREQYSWLLQEESHTSAKRHFLKEKIHRLAEARHTLSKFAQSLQG

MX2

Interferon-induced GTP-binding protein Mx2

710 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

81.452 kDa

MSMSFRPLKYKRHTQTSTQHHPKQDIYFHQQPPGPPLGQTMSPPQWQVEESNPDFLPNNFNQLNLDPQQPEAKGGQQMSKGPENNLYRKYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIITRCPLVLKLTKRECEWTGKITYRNITQQLQNPSEVEWEIRRAQNIIAGNGLGISHELINLEITSPEVPDLTLIDLPGITRVAVENQPQDIGLQIKALIKKYIQRQETINLVVVPCNVDIATTEALSMAQEVDPDGDRTIGILTKPDLVDKGTEKGVLKVMQNLTYHLKKGYMIVKCRGQQDITNKLSLAEATRKETMFFETHPYFRILLDEGKATVPLLAERLTTELIWHINKSLPLLENQIKEKHQRATEELQQYGDDIPSDEGDKMFFLIEKIKVFNEDIGKLIEGEEIVMETESRLCNKIREEFTSWILILTTNIEKVKSILNEEVSKYEKKYRGKELLGFVNYKTFETVVKHYLGQLIDPALKMLQKAMEIVWQTFKDTAKKHFAEFCNLHQTVQNKIEDIKTKQMAEAANLIQLQFRMEKLVFCQDQIYGVVLNKVREDIFNSMGKASETPQSKQPFLNDQSSISSIVEIGVHLNAYFMETSKRLANQIPFIIQYFMLQENGDKVQKAMMQLLQDTQHYSWLLQEQSDTATKRKFLKEKIFRLTQAQQALYEFPHFKG

MX2

Interferon-induced GTP-binding protein Mx2

710 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

81.335 kDa

MSLSFRPLKYKRHTQTSTPHHPKQDIYFHEQPPGPPLGQTMSPPQWQVEESNPGFLPNNFSQLNLDPQQPEANGGQQRSKGPENNLYRKYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIITRCPLVLKLTKRECEWTGKITYRNITQQLQNPSEVEWEIRRAQNIIAGNGRGISHELINLEVTSPDVPDLTLIDLPGITRVAVENQPQDIGLQIKALIIQRQETINLVVVPCNVDIATKKYTEALSMAQEVDPDGDRTIGILTKPDLVDKGTEKGVLKVMQNLTYHLKKGYMIVKCRGQQDITNKLSLAEATRKETMFFETHPYFRVLLDEGKATMPLLAERLTTELIWHINKSLPLLENQIKEKHQRATEELQQYGDDIPSDEGDKMFFLIEKIKVFNEDIGKLIEGEEIVMETESRLCNKIREEFTSWILILTTNIEKVKSILNEEVSKYEKKYRGKELLGFVNYKTFETVVKHYLGQLIDPALKMLQKAMEIVWQTFKDTAKKHFAEFCNLHQTVQNKIEDIKTKQMAEAANLIQLQFKMEKLVFCQDQIYGVVLNKVREDIFNSMGKASETPQSKQPFLNDQSSISSIVEIGVHLNAYFMETSKRLANQIPFIIQYFMLQENGDKVQKAMMQLLQDTQHYSWLLQEQSDTATKRKFLKEKIFRLTQAQQALYEFPHFKG

Mx2

Interferon-induced GTP-binding protein Mx2

659 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

75.074 kDa

MVLSTEENRSVDLVNLPSVPLPDGEAGVGENNKDSLNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLNQGEEWKGKVTYDDIEVELSDPSEVEEAINTGQNHIAGVGLGISDKLISLDVSSPHVPDLTLIDLPGITRVAVGNQPADIGRQIKRLITNYIQKQETINLVVVPSNVDIATTEALSMAQKVDPDGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRALLEDGKATVPCLAERLTMELISHICKSLPLLENQIKESHQSTSEELQKYGADIPEDENEKTLFLIEKINAFNQDITAIVEGEEIVREKECRLFTKLRKEFFLWSEEIERNFQKGSDALYKEVYTFEMQYRGRELPGFVNYKTFENIIRRQIKTLEEPAMEMLHKVTEIVRAAFTTVSEKNFSEFFNLHRTTKSKLEDIRLEQETEAEKSIRLHFQMEQIIYCQDQIYRKALQKVREEEAEEEERKHGKSRSSQSKNLQTSSMDEIFQHLNAYRQEAHNRISSHIPLIIQYFILKMFAEKLQKGMLQLLQDKDSCSWLLKEHSDTSEKRRFLKERLARLAQAQRRLAKFPG

Mx2

Interferon-induced GTP-binding protein Mx2

655 amino acids

Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV) and Hantaan virus (HNTV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

74.292 kDa

MVLSTEENTGVDSVNLPSGETGLGEKDQESVNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLNEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDRGTEDKVVDVVRNLVYHLKKGYMIVKCRGQQDIQEQLSLTEALQNEQIFFKEHPHFRVLLEDGKATVPCLAERLTAELISHICKSLPLLENQIKESHQSASEELQKYGMDIPEDDSEKTFFLIEKINAFNQDITALVQGEENVAEGECRLFTRLRKEFLSWSKEIEKNFAKGYAVLYNEVWAFEKQYRGRELPGFVNYKTFENIIRRQIKTLEEPAIEMLHTVTEIVRAAFTSVSEKNFSEFYNLHRTTKSKLEDIRLEQEKEAEMSIRLHFKMEQIIYCQDQIYRGALQKVREEEAEEEKKTKHGTSSSSQSQDLQTSSMAEIFQHLNAYRQEAHNRISSHVPLIIQYFILKMFAERLQKGMLQLLQDKDSCSWLLKEQSDTSEKRKFLKERLARLAQARRRLAKFPG

mx2

Interferon-induced GTP-binding protein Mx2

635 amino acids

Does not inhibit strain RB-1 of the fish pathogen, infectious hematopoietic necrosis virus (IHNV).

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

72.113 kDa

MNYTLNQHYEEKVRPSIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKKEGEEWHGKISYQDREEEIEDPSDVENKIRKAQDEMAGVGVGISDDLISLEIGSPDVPDLTLIDLPGIARVAVKGQPENIGEQIKRLIRKFITKQETINLVVVPCNVDIATTEALKMAQEVDPDGERTLGILTKPDLVDKGTEETVVDIVHNEVIQLTKGYMIVKCRGQKEIMERVSLTEATEREKAFFKEHAHLSTLYDEGHATIPKLAEKLTLELVQHIEKSMPRLKEQIEEKLEETRTALEKCGTGPPEDPKERLYFLIDKVTLFTQDAINLSTGEELKSGDINVFSTLRTEFGKWKAYVDRSGKNFNKKIEKEVADYEKRYRGRELPGFINYKTFEVIVKDQIKQLEEPAVKKLKELSDAARKAFILLAQNSFTGFPILLKTAKTKIETIKQEKESTAESTLRTQFKMELIVYTQDSTYSSSLKKRKREEEELEEGELVKNNLGSWKGLPVVSVRSTVNGLDTHATLREMMLHLKSYYHIASQRLADQIPMVIRYLVLQEFASQLQREMLQTLQEKDNIEQLLKEDIDIGSKRAALQSKLKRLMKAHNYLVEF

mx2

Interferon-induced GTP-binding protein Mx2

625 amino acids

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

71.849 kDa

MSLSEQYEEKVRPCIDLIDSLRALGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKKSRKADFWHGKIKYEDYEEEIEDPADVEQMIRKAQNEIAGTGMGISDKLISLEVTSSNVPDLTVIDLPGITRVAVKDQPENIGDQSKRLIKKFITKQETINLVVVPCNVDIATTEALKMALEVDPNGERTFGVLTKPDLVDKGSEETVVSIINNEIVYLNKGYIIVRCRGQQEIKDRVSLNETVKRERDFFEDHPHFRTLYDNRKATIPNLAEKLTLELVFHIGRCLPRLEERIQVKLSETQAELDRYGSGTPTEPEQRIYFLTDKITAFIQDVLNLTTGEEVKSMLYMNIFPDLRKQFDLWKNDLDSVGETFNKKIEKEMKAYEEKYRGRELPGFLKYNTFEVIVKGQIKQLEEPAIRRLKEISDLIKREFSQLAHSNFPGFPNILKMAKTKIDNIKQVKESETESILRTQFKMEMMIYTQDKTHHDNLKMLKSKEEGKERQKLGVAHSPSHKLYDHSDSEGIREELTCHLKSYFSIVTKRLADQVPMVIRYMMLQESAAQLQREMIQLIQDRHNIEELLKEDHDIASKRNNLHSCQKRLTEALKYLAKF