MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876)

Length

744 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

84.897 kDa

Sequence

MNSNIEDDPWSSGWNDDNDNNNNNNTSINDPLTGATATTTPYQSSYLTSSQLFTSTGGGGSGSGGGYNSGVNTYNTTIPPNLINVPSSYETIYSHFITKYNNNNNNNNSNSTFTLNDFEINIIDKLISLNYLTNYQKQKILDIIYENNLLPINQSFKFYQILGLLALEIDVPGTGDYVTLQFRLNNNLPDLPEKFINEIINEENEQEEQTSGLLGNRNRSIQSHSHFGPNNQDDWNIDDSTTISGGGGGGGGNFGDPLLVDHSYIHDDLIDESRSVGGTQPQQGGGGGSGGGSGSGSGTIAPNVDSSYIEKYINDIKDQFKPLFSGIDLIKIKEVPEKEGIIFKHINYMITHDLKIGGTSSGTKKVIRRYSDFVWLMEYLLEKYPFRVIPGLPPKKFTGASPDSQFLQRRRRGLHRFLNQLIKHPILSQEPIVQSFLTVPTDLTTWKKQAKIDSSLEFKGQKIQTDFINVIWPIMGEPFLKKWRQAEENIQFIIDKWVKIIILVERYERRQQQISFDNGKFAEMLNGFSKLNTKIYPDNEDNNNSTRNDVNVNVVVVDNNENYKQDFDFNSSGDIININQCLNSIGEFFNKSSQVLIDESYIINTKTLEKFKNYLDYLNSLQELFERTKQLSINQIDLLDKRIKDQEIKFKKISEENPDIKGGELIKLRQSIINDKQEIFQQLNKDWLIKQCCLQEFIIFQETQFLITELWVEWCKDRLKCQEKLVGLYDNLNQEIIHDMPLER

Protein

Sorting nexin MVP1: MVP1

Gene

mvp1

Protein

Sorting nexin mvp1

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

Length

729 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

80.642 kDa

Sequence

MSLFGTSPDDPSMGDSVHQRSRSSLFADEPLPGGAGAGNSANLGSSSLFADDDGFQSSSPWNSNANKRAARHELVKTLLPDADVPESYIDAYDLVLNEGDRVGGVVGLTSVREILSSSGLSASDQAKIFNLVVSGDGDSANGLGRGQFNVLLALIGLAQEGEDLTFDAVDDRRKKLPLPKSSYLDRLRDRQQPSAPSHPEERPTTPPPPPAAINDPPSARSRQSRETLGGLDADPWGSPQLHRGHNHVQTEPEPPVLNGFGSVRSATNAWSSGAGEDETQHEVPSGLRANGRTDGAPSTSSGSGWGGSYRNTTAGDGFGGPIRAGLGNLGAPSSGQEEPNARRRLGIGISTSSQVEETVTVNLLPEKEGMFMFQHRNYEVKSSRRGSTVIRRYSDFVWLLDCLQKRYPFRQLPLLPPKRIAADSNSFLEKRRRGLVRFTNALVRHPVLSQEQLVVMFLTVPTELSVWRKQATISVQDEFTGRVLPPDLEDSLPANLTDIFETVRSGVKRSAEIYINLCTLLERLAKRNEGLAADHLRFSLALQSLTEVTKDTYAVDTNDVPILNEGIMATARHLSNSQSLLEDEARAWENGILEDLKFQRDCLVSVREMFDRRDRYARNNIPQLERRIESNERKLEELRTRPQGAVKPGEIEKVEESIFKDKESIVQQHARGVFIKECIRDELVHFQRSQYHISRLHQDWSQERVKYSELQADNWRSLSDQVEGMPLGE

Protein

Sorting nexin mvp1: mvp1

Gene

mvp1

Protein

Sorting nexin mvp1

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

724 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

79.918 kDa

Sequence

MSLFGTSPEDSSAGNSAHRSKSSLFADEPSLGTGSNANLGSSSLFADDDDLSSGSPWNSNVNKRTARHKLVKTLLSDSDAPESYIDAYDLVLSAGDRVGAGIGLTSVREILSGSGISASDQEKILNIVVSGDIDSANGLGRGEFNVLLALVGLAQEGEDLTLDAVDDRRKKLPAPKSLYLDALRANQESGTPAPSQERPITPPRPASPQQAPNSAHSRRESMTGLESDPWGSPELHRGHAHAQLESDHPVLNGYGSVRSATNAWSSRVGEDNNPNEISNSNRANSQTDSAPSHGSGFGWGESLGNTPSDGGLGGTARAGLGGFGPPSSVHSDSNPRRRSLGIGRVASPPVEEHVTVTLLPEKEGMFMFQHRNYEVKSARRGSTVVRRYSDFVWLLDCLQKRYPFRQLPLLPPKRLSADSNAFLEKRRRGLVRFTNALVRHPVLSQEQLVIMFLTVPTELSVWRKQATISVQDEFTGRDLPPDLEDSLPSTLPDTFETVRGGVKRSAEIYINLCTLLERLAKRNEGLAADHLRFSLALQSLTEVTRDTYAIDTNDVPLLNEGIRATANHLSVSQSLLEDEARAWEEGVLEDLKRQRDCLVSVREMFDRRDRYARNNIPQLERRIENNERKLQDLRSRPQGTVKPGEIEKVEDAIIKDKESIVQQHARGVFIKECIRDEIVYFQQSQYHISRLHQEWSQERVKYAELQADNWRSLSDQVESMPLSG

Protein

Sorting nexin mvp1: mvp1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Ustilago maydis (strain 521 / FGSC 9021)

Length

683 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

77.206 kDa

Sequence

MSRHHRPFTWGGAQPGASFSNPTSPTLEASTFGFEPSVPDIYRRAWILVTKDASAELFADTSDADIHLGLLHKLLTSAGGLGPGSAEQIVNSACKGSRCSRSDFYCALGLLHQMQQGEELDVHLVQQRLTMGSLSAPVLDLSDATLNPHSHHTFPPTAPSGPSRIDPRPSTFMREMSDPWNANSSGSYNGIDTRPAYNQYDAMPQQYDTLNSHDSALPAGFAGNVSSGSFERIKFNAGDDRRSHQLLAHNQGSSTDTFLAPDRTEARARQPNTRQERPFSYMSDTAETNAVDAAEDPAADLPEDQVTVRLRSELEGFIIKHNVYIVSSSLRKSQVTRRYSDWLWLAECLVKRYPFRCLPVLPPKRIAMPIAGRHLSADDLFIERRRRGLERFLRMLTCHPMLREDKLVEVFFTEPRPIAEWKSSAPALFLDEEGLIKTVDEAERMSIPEDLQLKLTQQRQAIPELLERWTAMVALFERIVKRNDAAAADYSRLNFSLLSVIETSARRWRPGSDNGKKTEEIMSTMASIFQDHSDTTSSRVSAVSLSTLEGMKAQRDLILSFRDLIGRIDRQLVDPIDMLKKRIEASQKRITTLAASANSNSASIQQEQATLSAQVKQDTQSIQKYLNRRIHAKKTVWEELIWFHHRFKAVEEDMQKFVRDETFFLSTLTRMWEATEMKMKMIR

Protein

Sorting nexin MVP1: MVP1

Gene

mvp1

Protein

Sorting nexin mvp1

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

664 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

76.861 kDa

Sequence

MGDNVFLEPDPWASSSNWGSPVKPLNYKTAIGNSSIPLQYRNYWDVFQANNVLLFPEEESYSDIFHVPQDVMKEFFTLIESSSNQPLRQIQFFVLLALVACYQLGVPSTLEQIFKQRNVLPILQRFNPELFNRSSDNETPLFPNNSPPASTTALNLSSNIVPSINESKILEQEDDDVSNKSLPHAQQSIIRSFPDIQKQPKGFFSYPSSTVSSIAPSTLEAGNLHSQQPPKFSVDSSVDDNAITPRKPFSKIPNRLSPSTQPLLSNSRHSSFRLASSSTSFPASLEMNVDIDLEPSGYFFYRHNNYIISDSSNTREVLRRYSDFFWLHSYLMKKYPFRRVPLIPLKKFHSKCFNSKQFFRTPPPGLSDFVNDLSHHPIFSNDEVVRVFFTEPNVFKNWRRENQKRIDQEIEQFLVVPQSQVPDASETVKERLLKLNMSTTTAINNQLNIFRIFEKMIFTLQHFHEDFLRLQNSFNCLLDSGLYHQVFTSTFAQNESKIMSMASGHFYNIDSLLHQQNDAVKHTFLLGLSKEIKILISLRLLIERISEVFSTDLTKVRHTISNDENLLRETANSDESGRNRTFLNRSSKKRAENSLKSKKELYLKNLNQRYQIAHELEQELSYLQDYVFSLGNPYVEYCKQHVKLEEESLKIWHTLESDFSRLET

Protein

Sorting nexin mvp1: mvp1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

Length

612 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

67.744 kDa

Sequence

MFNAPRPMASSYSYTDPLSNSAAAGAAFGELDPWSSAPSPAGSVTPARATASASEGRNIAANGNKEEGLNGLINDPPALYVSLLDQLDTSGTGEVSLAAVHRLLGTSKLPAVVVEKIIHLTSRDKSTLTRPEFFCALALVSLAQSSPDPNDISIEKLSFSLSNLPLPKLKPSDPPSVSSGVAASTAAATGFNAWDGTINKGTTYSANNSTFRSTDPMVDNAEDRWWKDQERIVVTLIPEKEGWFLQKYRIESDKRGEGPVARRYSDFVWLMDVLEKRYPFRILPPLPPKRINPSSAFLEARRLALIRLLSFLTAHPVLRTDACLNIFLTSSSFESWRKRTPVSTDEESLSKKLTTAQEMSIPSDLELKLDNLRERLPAMLGHYTRLVVMAERSLVRLQVQAAEAARMAMSTQSIGELVPRCCWRSVQGDDGESGRGVARECGLCEGVGRGWGDVGDGWVSVGEELEKGVQLLQKHIESLKSQRDLYSSFHALFYRHNKLSLDNVDVLRKRVDSRFSKIESLKSAKKPGWEGEVDKLASQSDRDTAEIQRLLARRVFVRACMWHELSVVFHSMQAAQGTMGWKDFVKDQKERTKRLNGVWQGLEETLESMPLE

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)

Length

612 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

67.744 kDa

Sequence

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

605 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

68.061 kDa

Sequence

MSLFSAATTAVERTGYGSRYDHIFDMFHPIDGRIPAVCYKRLLETINVSGEDKDRLATLAGSILEGGDGSGGILTSSFTRESWRAALLLANVAQDGLPFDDPSQLVNVDTLTPMDFSEEGERSSINFSASTTGRSQTPLFGDDLDDHSIQSSRSESIIHNNGHSRGHSALDWNPEEQEALQQSQLSQSQLSRSTTPPPLNPQALVPESESGVWTAPPRPDFAPNKADSVTLAIVPEREGMFLFRHVNYSISSVSGTDRITVIRRYSDFSWLQDYLLKKYCFRQVPLLPPKRLAVNGHYLSSDNYFLERRRRGLTRFINQVLRHPVLGQDEAVRTFVTLRNDISGWKKSVFNTAREEFNGRTIDPKFVQQWDEQQATALWAGLIVELDRSHDSVVQLCVLLDRVAKRQEAQAVDSAKIAYNLGAALPPSARVLYSVADDGCVQQITRGLSRASARIETDCQLQQDEARGSQVGVLEEAKKYREALGSMRELFDRLEKYGGNNIPLLEKRIQQNQGRVTLARQRKALMSEIEKLDRAIKMDTEMIAAHKNRTWLIRECITEEIGLFQKTQLQISKLLQEFCVDKIKYAELYSDNWGGLDNDVMDLPV

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

523 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

60.619 kDa

Sequence

MMDLDSQELWGRGPSMESPNNAWASVQRTPADSARTQQIVSPVVRQAESLGSLTLTDSSLSAEVKETMRNNYNERKMYEPGTPALEQTVWGAPPSQLDASISGLDTSMAPVASQSSMCDELHSEDLENWMNSRRKTYNPLAKNIVVVEEIPEREGILFKHTNYLVKHLVVLPNTNPSSNQTVIRRYSDFNWLQEVLLKKYPFRMIPELPPKKIGAQNADPIFLARRRKGLCRFINLVIMHPVLKQDDLVLTFLTVPTDLGSWRKQANYDTTEEFTDQKIDKAFISLWHKELSNQWNKADAKIDELLESWIKTSVLVERYERRMRQVSEERRLLGRVIEEFADNSVTLYPLEEGTIHDINSHISTISKHLNSLADTSKKERQEVEEHLSVKFKTFIDIIIALKGVFDRYKIMAGNNIAHLQRRVEINMDKLQSMESNPDVKGAEYDKLRQTIQRDKRTIAEQLNRSWLIRKCILEEFVIFQETQFCITHVFQEWAKMHVKYANETTESWEKVYANLQDMPLSRS

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

512 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

59.656 kDa

Sequence

MDLEADPWRVNSEENGNNISGSVWEPDNSSVNALKSYSADSLQQEANKRVNDDYLGVNIFSNGDNIVRGTASNVYQNDVLWDRPNIGSTTQETDIRGVNRFQATDTPQYAANDEYKNWVESVRKTYFPLAEDIVSVEEIPEREGLVFKHTNYLVKHLTPLPNTDPSDDRTVVRRYSDFDWLQDVLLRKYPFRMVPELPPKKIGSQNADPLFLAKRRKGLSRFINLVMKHPVLRSDDLVLTFLTVPTDLSGWRKQAHYDTTDEFTDKHISSSFMNLWRKEFSEQWNKADERIDIALDTWVKVTVLIERYEKRMKQVAHERKLLGQILNAIPDTTEALYPQSTATVSQINEGVGLIVEHLNSCADVIERENEEVDSGLSVRFKAFIDVIIALKGLFERYKMMAGNNIPQLQRRVEINQERLNTLESNPDVKGAEYDRVKQSISRDKRSILDQMNRSWLIRECILEEFTIFHETQFLITDCFQRWIEINLRYTNNNVDNWEKICKKLRDMPLQRH

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

511 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

59.657 kDa

Sequence

MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTLNFSTPLDTNEEDTGFLPTNDVLEESIWDDSRNPLGATGMSQTPNIAANETVIDKNDARDQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLLFKHANYLVKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVRTDLTSWRKQATYDTSNEFADKKISQEFMKMWKKEFAEQWNQAASCIDTSMELWYRITLLLERHEKRIMQMVHERNFFETLVDNFSEVTPKLYPVQQNDTILDINNNLSIIKKHLETTSSICKQETEEISGTLSPKFKIFTDILLSLRSLFERYKIMAANNVVELQRHVELNKEKLESMKGKPDVSGAEYDRIKKIIQKDRRSIIEQSNRAWLIRQCILEEFTIFQETQFLITRAFQDWAKLNSNHAGLKLNEWEKLVTSIMDMPISRE

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Sorting nexin MVP1

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

509 amino acids

Function

Required for vacuolar protein sorting.

Similarity

Belongs to the sorting nexin family.

Mass

59.105 kDa

Sequence

MDTYSGQNGWADTSNASPWGDTNDTMPIDNSLSNSLSGLQLNEDINTVRANLTESIWGTERTGAPNNVETGLEAKDSLNVSTNFNELNTAILSPTSSTSNIEEQNSFTESLESWINEVRKTYNPQQLDIISIEEIPEREGLLFKHANYSVKHLIDLPNTEPPKNRTVVRRYSDFLWLQEVLLKRYPFRMIPDLPPKKIGSQNLDPVFLNKRRIGLSKFINLVMKHPKLSKDDLVLTFLTVPTDLTSWRKQVSYDTADEFTDKRISKDFVKIWKKDLAEIWNNTANCIDELIDKWTKISILVDRHEKRLQIIANERKIMNDLIHDVGNLTKSVYPIDQNPTILDINSGMTVISKHIEKTNENYNQQALDTKQKVLPKFRMYTDILRALKNVFERYKMLATNNVSMLQKHIDLNLQKLEDMKGKPDASGQEYDRIKTTIRKDRKIMYEQSNRAWLIRECILEEFTIFQETQFMITGCFQEWAKVQSTYSSLNLNEWENVTNHILEMPLSRE

Protein

Sorting nexin MVP1: MVP1

Gene

MVP1

Protein

Inactive GDSL esterase/lipase-like protein 25

Organism

Arabidopsis thaliana

Length

417 amino acids

Function

Involved in organization of the endomembrane system and is required for endoplasmic reticulum morphology and organelle distribution. May act by inhibiting the formation of PYK10 complex by binding to GLL23 and exporting it from the ER. Required for proper subcellular localization of myrosinase TGG2. Has no lipase or esterase activity.

Similarity

Belongs to the 'GDSL' lipolytic enzyme family.

Mass

46.083 kDa

Sequence

MLLIPSFTANSNEPPPSKLSLSDLSMAILKSHFFLLFPLLLLHFHTVSFAQTLFVFGDGLYDAGNKQFLSQNRVDASFPPYGVTVGQATGRWSDGSIVPDYLAKFMGIPKISPILLTTADFSHGANFAIADATVLGSPPETMTLSQQVKKFSENKNKWTNQTRSEAIYLIYIGSDDYLSYAKSNPSPSDTQKQAFVDQVITTIKAEIKVVYGSGGRKFAFQNLAPLGCLPAVKQASGNVQECVKLPSEMAALHNKKLLQLLVELSRELNGFQYSFYDFFSSIQNRVIKSKTYTFETGNAACCGTGSINGSNCSAKNVCAKPEEYIFFDGKHLTQEANLQVGHLMWGADPEVIGPNNIRELMVLPLDITVILAGIQEAMAAMRPRQSNIESLYDIKKMESEMDNHWLYQVDKAISFMI

Protein

Inactive GDSL esterase/lipase-like protein 25: MVP1