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MVB12A

Gene
mvb12a
Protein
Multivesicular body subunit 12A
Organism
Danio rerio
Length
275 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
29.766 kDa
Sequence
MSVCDSSIRPVSAMAWASNTSTCPGHFTLISQTEDGASANFSRGFVRSGYFLCYSKDLSGGMVVADVQVITDKGTILHGYCYIPEYLEQKASVAKKKRVCVRLVPVGSVTTAVLDLKLTTKHKSMVQQYTCLGDMNGFVVWCLKGPFSPPAPQAKPRRVSLDIRSLSLDGPAPPQPLKPSNPPEAPPKVSRRRSKLDLPAGGVCDSSVCSGISAMDGVPFTLHPKFESRSSSTKVSVITLSDIRIKSVQDIENEYNYTFTVEELAAKRIRPSLSG

Gene
mvb12a
Protein
Multivesicular body subunit 12A
Organism
Xenopus laevis
Length
275 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
29.897 kDa
Sequence
MENSSTPITGLAWISSVTLCPKTYNMIVATVEGASANFVKGFNQKSAVYLGYSTVPEGLEQVITDIQMLNEKTVLPVGYAFIGEHLDPKISVPKKKRLCVKQMPMHTAETAVCEIKLSMKSKQFGAPYERIGEISGLVFWCRKGSVSAPKPTPKPRNITSGIKGLSLDSNTAVQPVRRASAPNPDAGQAVPLSNGKWGLSENAIYDSSNIYGISAIDGIPFTIHPMFENTINNSSVAASDFRDLHIKTLSEIESEYNYGFVVEKTAAARIPPRLR

Gene
MVB12A
Protein
Multivesicular body subunit 12A
Organism
Bos taurus
Length
273 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
28.906 kDa
Sequence
MDPGPGANGMPLAGLAWSSASAPPPRGFSAISCTVEGTPASFGKTFAQKSGYFLCLNPLGSLENPQENVVVDIQILVDKSPLPPGFSPVCDPLDSKASVSKKKRMCVKLVPLGAADTAVFDIRLSGKTKTVPGYLRVGDMGGFAIWCRKAKAPRPVPKPRALSRDVRDLSLDSPGQPSKGGFPERTLSRLGSRASTLRRNDSIYEASNLYGISAMDGVPFTLHPRFEGKSCGPLAFSAFADLTIKSLADIEAEYNYGFVVEKTAAARLPPSVS

Gene
MVB12A
Protein
Multivesicular body subunit 12A
Organism
Homo sapiens
Length
273 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
Similarity
Belongs to the MVB12 family.
Mass
28.783 kDa
Sequence
MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLGSLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFGDLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS

Gene
Mvb12a
Protein
Multivesicular body subunit 12A
Organism
Mus musculus
Length
271 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
28.705 kDa
Sequence
MDPGTDSAPLAGLVWSSASAPPPPGFSAITCTVEGGTASFGRGFAQKAGYFLCLSTLGIPENPQDNVVVDMQIVMDKGPLPSGFSAVNDPQDIKASVSKKKRMCVKLMPLGTADVVVSDVKLSGKTKTVPGYLRVGDIGGFAIWCKKSKAPRPVPKPRTLSQDMRGLSLDPPKEPSKGSHPERTLSRLGSRASTLRRTDSIYEASSLYGISAMDGVPFTLHPRFEGKSCGPLNLSAFGDLTIKSLADIEKEYNYGFVVEKTAAARLPPSVS

Gene
Mvb12a
Protein
Multivesicular body subunit 12A
Organism
Rattus norvegicus
Length
271 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
28.752 kDa
Sequence
MDPGTDSTPLAALVWSSASAPPPPGFSAITCTVEGATASFGRGFAQKAGYFLCLSTLGIPENPQDNVVVDMQIVMDKGPLPPGFSTVNDPQDARTSVSKKKRMCVKLMPLGTADVVVSDVKLSGKTKTVPGYLRVGDIGGFAIWCKKSKAPKLVPKPGTLSQDMRGLSLDQPKEPSKGSHPERTLSRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCGPLNLSAFGDLTIKSLADIEKEYNYGFVVEKTAAARLPPSVS

Gene
MVB12A
Protein
Multivesicular body subunit 12A
Organism
Gallus gallus
Length
267 amino acids
Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
Similarity
Belongs to the MVB12 family.
Mass
28.063 kDa
Sequence
MAAEEEAAPLSGVGWAAGPESAPAGWSVITISVEGSAANLGKGFGHKGGYLCVSTAAPGSAGPVVTDVQVLSDRNPQPAGYSRAPEFPEPRSGVSRKKRLYVRLQPRGAAETAVFDIKLSGKSRAVPQYMKIGEIGSFAIWCKKGALPQCSPPPVPKPRTVSLGLKQLSLADSEQQAPGKPVAQSGSRHASFTLHNSADDGSSIYNLSAMDGVPFTLHPKFERSPKSDSSAILTDLTVKSLADIEKEYNYTFVVERTAAARLPPSIC