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MTNR1A

Gene
MTNR1A
Protein
Melatonin receptor type 1A
Organism
Ovis aries
Length
366 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
40.401 kDa
Sequence
MAGRLWGSPGGTPKGNGSSALLNVSQAAPGAGDGVRPRPSWLAATLASILIFTIVVDIVGNLLVVLSVYRNKKLRNAGNVFVVSLAVADLLVAVYPYPLALASIVNNGWSLSSLHCQLSGFLMGLSVIGSVFSITGIAINRYCCICHSLRYGKLYSGTNSLCYVFLIWTLTLVAIVPNLCVGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVVFCYLRIWALVLQVRWKVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASDPASMAPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVADRIKRKPSPLIANHNLIKVDSV

Gene
Mtnr1a
Protein
Melatonin receptor type 1A
Organism
Mus musculus
Length
353 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
39.837 kDa
Sequence
MKGNVSELLNATQQAPGGGEGGRPRPSWLASTLAFILIFTIVVDILGNLLVILSVYRNKKLRNSGNIFVVSLAVADLVVAVYPYPLVLTSILNNGWNLGYLHCQVSAFLMGLSVIGSIFNITGIAMNRYCYICHSLKYDKIYSNKNSLCYVFLIWMLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMIIVIFCYLRIWVLVLQVRRRVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNLIGLIVASDPATMVPRIPEWLFVASYYLAYFNSCLNAIIYGLLNQNFRKEYKKIIVSLCTAKMFFVESSNEEADKIKCKPSPLIPNNNLIKVDSV

Gene
MTNR1A
Protein
Melatonin receptor type 1A
Organism
Phodopus sungorus
Length
353 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
39.685 kDa
Sequence
MKGNGSTLLNASQQAPGVGEGGGPRPSWLASTLAFILIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAIADLVVAIYPYPLVLTSIFNNGWNLGYLHCQISAFLMGLSVIGSIFNITGIAINRYCYICHSLKYDRLYSNKNSLCYVFLIWVLTLVAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMIIVIFCYLRIWILVLQVRRRVKPDSKPRLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLIVASDPATMAPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRQEYKRILVSLFTAKMCFVDSSNDPADKIKCKPAPLIANNNLIKVDSV

Gene
MTNR1A
Protein
Melatonin receptor type 1A
Organism
Homo sapiens
Length
350 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
39.375 kDa
Sequence
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV

Gene
MTNR1A
Protein
Melatonin receptor type 1A
Organism
Bos taurus
Length
257 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
29.37 kDa
Fragment
single
Sequence
YPLALASIVNDGWSLSSLHCQLSGFLMGLSVIGSVFNITGIAINRYCCICHSLRYNKLYSSTNSLCYVFLIWMLTLVAIVPNLCVGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVIFCYLRIWALVLQVRWRVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASEPASMAPRIPEWLFVASYYMGYFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVAHRIKRKPSP

Gene
Mtnr1a
Protein
Melatonin receptor type 1A
Organism
Rattus norvegicus
Length
156 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
18.214 kDa
Fragment
single
Sequence
CYICHSLKYDRIYSNKNSLCYVFLIWTLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIALVVFHFVVPMIIVTFCYLRIWILVLQVRRRVKPDSKPKLKPQDFRNFVTMFVVFVLFALCWAPLNFIGLIVASDPATMAPRIPEWLFVASYY

Gene
MTNR1A
Protein
Melatonin receptor type 1A
Organism
Sus scrofa
Length
154 amino acids
Function
High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
17.9 kDa
Fragment
single
Sequence
YCYICHSLKYDRWYSNRNSLCCVFLICVLTLVAIVPNLCMGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMVIVIFRYLRIWVLVLQIRWRAKPENNPRLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMAPRIPEWLFVA