MTMR4

Myotubularin-related protein 4

1195 amino acids

Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

133.353 kDa

MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVDSGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPESSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVKSPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS

Mtmr4

Myotubularin-related protein 4

1190 amino acids

Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity).

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

132.885 kDa

MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRATDALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHIACKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRASGGSLSTGTNDASEACDTDFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVLFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENAEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPGSDVVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHSQEVRGSLEPWHSSPEGAETVIDSGVGSPQLTVGEMGLPPPLPSSQKEYLSNKPFKGHKSCSLSYKLLNTSVSWEMKSNTSDIKVLEETEALAPDPSAQEEQGRTSDGLGKPPEQFLEKEAVSSLCSVSSKCGGACDFPEPPQDPLTGTPQQPHLDSMQISPSRCTPDHSQGSLCNPPSVASQTPEPNTDLLSQDPPGSTASISHQEQPSSVPDLIYKKEDAGKRGSKNGQLLENPRFGKMPLELARKPISQSQISEFSFLGSNWDSFQGMMTSFPSGETTPRRLLAYGCCSKRPSNKHIRAAGPCLGGQWAQREGMKSPVCSSHSNGHCTGPGGKNNRMWFSSHPKQVSSTKPSLLSCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYRQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCFNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQHLKKPIATASS

mtmr4

Myotubularin-related protein 4

1078 amino acids

Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity).

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

122.251 kDa

MGDEPPSLEYIQAKDLFPPRELVKEEEKLQVPFPVLPGEGVEYLGSANDAVIAISNYRLHIKFKDSVVNVPLRMIEAVESRDMFQLQIICKDSKVVRCHFSTFKQCQEWLKRLSRATLRPAKQEDLFAFAYHAWCQGVCTDEEEPLIHLCRPGDHVKSRFQIELKRMGFDLQNAWRVSEINNNYKLCQSYPQKLLVPVWITDKELENVATFRSWKRIPVVVYRHTRTGAVIARCSQPEISWWGWRNADDEYLVTSIAKACALNPAVRMPNGNPSNKGNNDGSDNSDTDFDSSLTACPVEGGGVPQKLLIVDARSYTAAVANRAKGGGCECEEYYPNCEVAFMGMANIHSIRNSFQYLRAVCNQVPDPGNWLSALESTKWLQHLSAMLKAATVVASAVDREERPVLVHCSDGWDRTPQIVSLAKILLDPYYRTLEGFQVLVETDWLDYGHKFADRCGHQENREDQNEQCPVFLQWLDCIHQLLFQFPCHFEFNHAFLVKLVQHTYSCLYGTFLANNLCEREMRNIYKRTCSVWSLLRTGNKIFHNLLYMPGSDLVLHPVCHVRALQLWTAVYLPATSPCTPMDDRMEMYLTPASQGPQFHARSLVRLPKTRSMDNLLTACDSGGLLTRTSSDPNLNNHQGNLESCSSSKEGNETEICDIQQQALSIEPKEEDGNDSKSTDHENEDSGSATNQNNNEQNALNNILSIAKPDSIQCKRDRFKSVLEKSSVIPVPSNEGTITDDNSHSNGTSEHLPVPALVTNGSVQNKSCVDVSKAMKLSTELSRTDKKPVFQTQRDEFSFCTSNWDSLPGMMRSVPICEVGLRRPLSYDCSTRSQHSRNGRHTMKLTGNLPASFHCSGPFTKRCRCVMACHTKQVQGSRFLPLACPSPAPLIYQDDDGLPIPSDVVQQRLRQMEASYKQEVDLLRRQVWELQLQLEIRQYCAPPSEPEADYEDDFTCVKESDGSDMDDLYSDKSEDRLSEASWEPVDKKETEVTRWVPDHMASHCFNCDCEFWLAKRRHHCRNCGNVFCAACCHLKLPIPDQQLYDPVLVCNTCYDHIQVSRARELMSQQLKKPLTAASS