About Products Protein Database Contact

MTERF4

Gene
MTERF4
Protein
Transcription termination factor MTERF4, chloroplastic
Organism
Arabidopsis thaliana
Length
541 amino acids
Function
Transcription termination factor required for processing and steady-state levels of plastid transcripts. Required for splicing of the chloroplastic Clp protease (ClpP) group IIa intron. Required for maturation of 16S rRNA and 23S rRNA in the chloroplast. Essential for embryogenesis (PubMed:21464319). Required for the maintenance of the correct levels of transcripts in the mitochondria and chloroplasts.
Similarity
Belongs to the mTERF family.
Mass
61.549 kDa
Sequence
MKIRFCNGFTKPGFLLVHFEPPSFFAVRSRSLSDSTYGNLCNHKKRPGTGIGLTVQCAIANRRFSSRSLDSPRRERSSRSSSSSGRDRDRDKDKGRDSKSLYSRPSLLDMNKEKAANRAKVYEFLRGIGIVPDELDGLELPVTADVMKERVEFLHKLGLTIEDINNYPLVLGCSVKKNMVPVLDYLGKLGVRKSTFTEFLRRYPQVLHSSVVIDLAPVVKYLQGLDIKPSDVPRVLERYPEVLGFKLEGTMSTSVAYLVGIGVARREIGGILTRYPEILGMRVARIIKPLVEYLEVLGIPRLAAARLIEKRPHILGFELDDTVKPNVQILQDFNVRETSLPSIIAQYPEIIGIDLKPKLDTQRKLLCSAIHLNPEDLGSLIERMPQFVSLSESPMLKHIDFLTKCGFSIDQTREMVIGCPQVLALNLGIMKLSFEYFQKEMKRPLQDLVDFPAFFTYGLESTVKPRHKKIIKKGIKCSLAWMLNCSDEKFEQRMSYDTIDIEEVETDPSSFDMNTLMQPEREEESDSEYEEEEDDDDEEFA

Gene
MTERF4
Protein
Transcription termination factor MTERF4, chloroplastic
Organism
Zea mays
Length
494 amino acids
Function
Transcription termination factor required for processing and steady-state levels of plastid transcripts. Required for splicing of the chloroplastic group II intron. Required for the accumulation of 16S and 23S ribosomes.
Similarity
Belongs to the mTERF family.
Mass
55.231 kDa
Sequence
MMKSLLFSAHPTSLLLPAPRLRRLLRLRAASSASASAPPRADRRSPGTPSRRPSSSLYARPSLLDMERDRATRRADVDAFLTSLGVDPGELAGLELPVTVDVMRERAEFLGSLGLTQEDLAAYPLALGCSVRKNMVPVLDYLGKLGVRRDALPDLLRRYPQVLHASVVVDLAPVVKYLQGMDVRPTDVPRVLERYPELLGFKLEGTMSTSVAYLVGIGVGRRQVGSVITRFPEVLGMRVGKIIKPFVEHLEGIGLQRLAIARIIEKKPYVLGFGLQEKVKPNIEALVDIGVRKEALASIVMQYPDVLGLELRDKLVAQQSLFESSILVSREDFGRVLERMPQAISLGRAAVLKHVNFLTACGFMLSQVSKMVVACPQLLALNIDIMRMNFEYFKNEMERDLEELVEFPAFFTYGIESTVRPRHEMVSRKGLTCSLAWLLNCSDAKFDERMKYDTIGVEEMEREDSSDMNASVDEVESEEYEDSDYGDSDDEFVR

Gene
MTERF4
Protein
Transcription termination factor 4, mitochondrial
Organism
Homo sapiens
Length
381 amino acids
Function
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S).
Similarity
Belongs to the mTERF family.
Mass
43.958 kDa
Sequence
MAAFGRQVLDWHRLIPLTWACMARQTPHLGEQRRTTASLLRKLTTASNGGVIEELSCVRSNNYVQEPECRRNLVQCLLEKQGTPVVQGSLELERVMSSLLDMGFSNAHINELLSVRRGASLQQLLDIISEFILLGLNPEPVCVVLKKSPQLLKLPIMQMRKRSSYLQKLGLGEGKLKRVLYCCPEIFTMRQQDINDTVRLLKEKCLFTVQQVTKILHSCPSVLREDLGQLEYKFQYAYFRMGIKHPDIVKSEYLQYSLTKIKQRHIYLERLGRYQTPDKKGQTQIPNPLLKDILRVSEAEFLARTACTSVEEFQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE

Gene
Mterf4
Protein
Transcription termination factor 4, mitochondrial
Organism
Rattus norvegicus
Length
347 amino acids
Function
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (By similarity).
Similarity
Belongs to the mTERF family.
Mass
40.381 kDa
Sequence
MASLGRQVPEWHRLMALSWACLARQTCHFRKEKKMSPSLFCKLTTVPSRGNFQEFSSVRPKKYMQEPEHRTRLVPCLHEEQRTCMGSESLELERAISSLQDMGFAEAHIDSLLNIQPSVHPQQLLDIISELLLLGLNPEPVFMALKKNPQLLKLSATQMKRRSSYLRKLGLGEGKLKRVLSVCPKVFTMRQQDIDNIVKVLKEKCLFTVQHITDILHRCPAVLQEDPSELEYKFQYAYFRMGLTHLDIVRTDFLQYSIAKVKQRHIYLERLGRYQTPDKKGQTQIPNPSLKNILRVSEAEFLARTACSSAEEFEVFKKLLDQEEEESESHMSEEEEEEEEEEEEELP

Gene
Mterf4
Protein
Transcription termination factor 4, mitochondrial
Organism
Mus musculus
Length
346 amino acids
Function
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit.
Similarity
Belongs to the mTERF family.
Mass
40.249 kDa
Sequence
MASLGRQVPEWHRLLALSWACLVRQTPHLREQKQMSPSLSCKLTTVPGRGSFQEFSSITPQKYMQEPENRTRLVQCLHEEQKPCVDPESLEPEKVIRSLQDMGFAEAHIHSLFSIQPSVHPQQLLGIVSELLLLGLNPEPVFNALKKNPQLLKLSSMQMKRRSSYLRKLGLGEGKLKRVLSVCPEVFTMHQRDIDRVVKVLREKCLFTAQHITDVLHRCPTVLQEDPNELEYKFQYAYFRMGLTHLDIVRTNFLQYSITKIKQRHIYLERLGRYQTPDKKGQTQIPNPSLRNILRVSEAEFLARTACSSVEEFQVFKKLLDQEEEEESESHASEEEEEEEEEEELL