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MTERF1

Gene
MTERF1
Protein
Transcription termination factor 1, mitochondrial
Organism
Homo sapiens
Length
399 amino acids
Function
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
Similarity
Belongs to the mTERF family.
Mass
45.778 kDa
Sequence
MQSLSLGQTSISKGLNYLTIMAPGNLWHMRNNFLFGSRCWMTRFSAENIFKSVSFRLFGVKCHNTDSEPLKNEDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIASIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNNNLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAGLSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLVLICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIFLAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCNLSTLNITLLSWSKKRYEAKLKKLSRFA

Gene
MTERF1
Protein
Transcription termination factor 1, mitochondrial
Organism
Pongo abelii
Length
398 amino acids
Function
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand (By similarity).
Similarity
Belongs to the mTERF family.
Mass
45.65 kDa
Sequence
MQSLSLGQTSISKGLNYLTIMAPGNLWHMRNNFLFGSRCWMTRFSAENIFKSVSFRLFGVKCHNTDSEPLKNEDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIASIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNNNLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAGLSLGHNDPADFVRKIILKTLYLIQSTKRVKANIEFLRSTFNLNSEELLVLICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIFLAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCNLSTLNITLLSWSKKRYEAKLKKLSRFA

Gene
Mterf1
Protein
Transcription termination factor 1, mitochondrial
Organism
Rattus norvegicus
Length
374 amino acids
Function
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand (By similarity).
Similarity
Belongs to the mTERF family.
Mass
42.937 kDa
Sequence
MASRNIWRVRRNFLFDLRGWVPQYSAEVFLKSIPFRPFSVECNSKDGENGDLLNNLLTMGVDVDMARRRQPGVFNKAVTNEQELKMFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWREIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTSAPRTFSNSLNLNKQMVEFLQETGISLGHNNPTDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLDKEDLLLLICGPGARILDLSNDCTKRNYTNIKKRLLSLGCTEEEVQKFVLSYLNMIFLSEKKFNDKIDCLLEEKISTSQILENPRVLDSSIHTLKTRIRELAHAGYDVSTSSIALLSWSQRRYEAKLKRLSG

Gene
MTERF1
Protein
Transcription termination factor MTEF1, chloroplastic
Organism
Arabidopsis thaliana
Length
284 amino acids
Function
Transcription termination factor required for plastid-specific rRNA accumulation and protein synthesis in plastids (PubMed:19563435). Essential for embryogenesis (PubMed:12324593, PubMed:19563435).
Similarity
Belongs to the mTERF family.
Mass
32.391 kDa
Sequence
MMIARCSLFPPPCFSAVRIRCFAGETSDTGILFREKLIYLQDLNVDPHKALRVNPSLRSAPISSVVSVETLLSSTGLSRPAVGRILDMFPDLLTSDPESEILPVLRFLSNEISISEQDIPKSISRCPRLLISSVDYQLRPALTFLKTLGFVGRDTITSRNTVLLVSNVERTLIPKIEYLEEGLGFTREEVAKMVVRSPALLTYSVDNNLVPKVEFFIEEMRGDVKELKRFPQYFSFSLERKIKPRHRLLKEHGILMPLSEMLKVSDGQFNHWLLELRLRSAERR