Protein
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol mannoside mannosyltransferase
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Function
Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM).
Similarity
Belongs to the glycosyltransferase 87 family.
Sequence
MLEMSKRQSPRGAGLAPTIAWRVFQLLTLAGVLWVGWRLLGRVPYRIDIDVYRMGGRAWLDGRPLYADGAIFHTQGGLDLPFTYPPLAAIAFAPFAWLSLPLASSAITATTLVLLIVATTIVLTRLDVWPHTTVTSEPAWMRRAWLAAAMVAPAVIYLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGLLLGLAIALKLTPAVFLLYFLLRRDIHTLLRTAATAVVASLAGFALAWSDSVEYWTETVRNTDRIGTATLNTNQNIAGALARLGLGESPRFILWVLACFAVLALTVWAARRALRGDTADQTTEAPVLALVCVALFGLVVSPVSWSHHWVWMLPVLVVTAVLAYRRRSVWFTALTAAGLALTVWTPITLLPEHRETTASLWRQLAGGSYVWWAFAVIVVIGLVSSSRTHTGDAHETDEPLVPLARGEAG