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MRPL18

Gene
MRPL18
Protein
39S ribosomal protein L18, mitochondrial
Organism
Bos taurus
Length
180 amino acids
Function
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (By similarity).
Similarity
Belongs to the universal ribosomal protein uL18 family.
Mass
20.397 kDa
Sequence
MALRSRSWELLPVCRNPGCRVAAFSTSAKPVVKPEADPVGNEAVAPEFTNRNPRNLELLAVARKERGWGTVWPSREFWHRLRVIRSQHHIEALVEHRNGQVVVSASTREWAIKKHLYSTKSVVACESVGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQIGMIEGGVVLQEPRRIYE

Gene
MRPL18
Protein
39S ribosomal protein L18, mitochondrial
Organism
Homo sapiens
Length
180 amino acids
Function
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Similarity
Belongs to the universal ribosomal protein uL18 family.
Mass
20.577 kDa
Sequence
MALRSRFWGLFSVCRNPGCRFAALSTSSEPAAKPEVDPVENEAVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQNGKVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIYE

Gene
Mrpl18
Protein
39S ribosomal protein L18, mitochondrial
Organism
Mus musculus
Length
180 amino acids
Function
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (By similarity).
Similarity
Belongs to the universal ribosomal protein uL18 family.
Mass
20.677 kDa
Sequence
MALRPRFWKCLSVCRKLECGFAALSTSSVPAVQPDVESKENEAVAPEFTNRNPRNLELLGVARKERGWATVWPNREFWHRLRVVKTQHHVEAFVEHLNGQVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLEAGINFMVYQPTPWEASSDSIKRLQNAMTESGVMLREPRRIYE