Protein
dTTP/UTP pyrophosphatase
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Sequence
MRRIILASASPRRKELLRQLIGDNFLVSPSSYEEPPQPDLAPEELLIRHSIGKARDVAKHFSSGIIISADTSVLYNGEVLGKPNFPEKAEEMLKKLNGRKFRVVTGLTVLDLDSAQEISESESTDVWMSEMDDEQILAYVRTGEPLDKAGAFAAQGKGAVLIERIEGDFFNAVGLPLFRLGKILEKLGVSVFDESFS