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MMS22L

Gene
MMS22L
Protein
Protein MMS22-like
Organism
Bos taurus
Length
1244 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA (By similarity).
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
142.274 kDa
Sequence
MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML

Gene
MMS22L
Protein
Protein MMS22-like
Organism
Bos taurus
Length
1244 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA (By similarity).
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
142.274 kDa
Sequence
MDNCPPASTFLTDSLELELQTEWCNPPCFSCDFDNRGGGKHFSGESYLSSGALKRVILNLDPLPTNFEEDTVEIFGIEWVTETALVNSSRVLFHLFRQQLYNLETLLQASCDFGKISTLHCKAHNIRQLCVTFLHYVKVFIFRSLQVRNAESHVPVHPYETLEAQLPSVLVDELHGLLLYIGHLSELPTTNTGAFVNQNQTKLYPPSWHLLHLHLDIHWLVLEILHMLGEKLKQVVYSHQFMNLAGDNLTNVSLFEEHCENLLCDLINLSLNRYDKKVRPSEALMSHHCPCPCIKELWVLLIHLLNHRSKWSLSESFWNWLNKLLKTLLEKSNDQRRSVLIVQPRDPLGFSWWIITHVASFYQFDRHGTPDEMRQMESNWNFVEELLKKSISVQDGILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPLKGLTYIIKSPLSMLEMVKTCCCDKQDHDLYKSSSSYTIFLCILAKVVKKAMKNNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLRLLDFLKPTFKTSPLIWKGQMAFLLMYTQKNLDIGVLAEKFSNAFREKAKEFLVSKNDEMGQRQTLWTLLSIYMDSVQEVFETSRCLHPSHEKLLNDGFSMLLRACQESELRTVLNFLQAVLARIRSLHQQLRQELQREHGDLSVQSSLSTKERHLAAVASALWRHFFSFLKSQRMSQIVPLSQLADAAADFTLLAMDLPSTAPSDLQPQPVTSMIQLFGWDDIIWPQVVARYLSHFLQNSMLCEALSHSGCVSFQALTVRSWIRCILQMYVKNLHVPDDSFIDINPEQAVEKDYMEQLTELTRLLFKLSEVKNIFSKSQVELPIPDDPKKALIRFFEAVGITYGNLQTVSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYTMMGTLVKSWALIFATSKAQKLLFRIIDCLLLPHTVLQQEKELPAPMLTAIQKSLPLYLQGMCIVCCQSQNTNAYLNQLLGNVIEQYIGRFLPASAHVLGLGQHPVLLALKNSASVPPMSLLKKCIVHVIRKSYFEFKGSLLPPRLASILAFILQLVKETNTDVSEIELLLPGVLKCLLLVSEPQVKRLATENLQCMVRACQVGSGGEPAAQLTSVFRQFIEDYGMRYDYQIYSILEAVAALDQQVVIHLVPTLTQSLKNSERKWGLGRNSAQREAYSKLLSQLGQVGQDEIQRLENDHIESML

Gene
MMS22L
Protein
Protein MMS22-like
Organism
Gallus gallus
Length
1243 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks.
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
140.908 kDa
Sequence
MDSFTPPLLSDSLQMAMEVENEKSNPPCFSCIFDNQNGGRSFSGESYLASGSLKRVLLRLDPSPNDYEEDAIEMFGFQWVTETALVESCGLLFGLLRQQIYKLEDLIEMNSSDFGKAANLHSEAENIRRLCINFLHYVKVFIFRYLEPPKTENDGVLHPYEELEAQFPSLLVEELHSLTLHIGHLCELPSNVLAAFTIQHQAKIFPPSWHLLHLHLDIHWLVLEILHVLSEKMMRQVVYANHFINLTGENLTNISLFETHCENLISDLISLSIQKYTKVRPSEALTSHHYPCNCIKELWILLIQLLGFRNKGSQTECFWSLVNKKLKSIFERPTSSESVSVFGTTQCKDPLSFSLWIVTHLASLYQFDRNGNLEEKKQKESNWKFVEELLKNSIGAQTGVLEEHLRMHLQCCLTLCRFWDWNLSVITILWDYYSKNLNSCFTVPWLGLKGLASISKTSLSMLELVKSCCCEQQIPTLYKSSNSYLIFLSILARMMKEEAESSGVHPWKQIKGRIYSKFHRKRMQELTEVGLQNFFNLFLLLAIVAETEDIVSRVLDLLDFLTPSLVSPSQRALIWRGHFAFLLIYVEKNMDISVLAEKLSNAFRVKAKEFLVTKNDYTQKQNLWTLISTYIDGVQEVFETSCYLSLSEEKLLNDGFTMLLPACRGAELSMVLNFLQVVIARLRSVHKRVSQGLQPGNADSNAQLPLVAKEHHLAVASALWRNFFPYLKSQRMSQTPPSPQLADTAAGFALLALDIPSKALSDLQPQPVLSMMQLFGWDDMVWPHLVSRYLSHLIQNSALCEAFSTMGYTSYEALTVRSWFRCVLQMFIDQPSGTLAKTDAERTVGKAYMEQLTEMTRLIFKLKEVESILSKARVEEPVLKQDPKNALVQFIKAVGRTYSGLQTLPEKSAMVLKALEYLGDVLKYVKPYLKAKGPPEGLQLAYWIIGCLVKFWAPILATSKAQQLLFRIIDCLLLPHSVLQQDKELPGALLSAIQESLHLYLQGLSFICCQSQARGAYLNQLLGSIVQQYFGRFLPPSPTALGAGQHPMLTALCSSITVPQALRLRKTTLHVINEHYMQFKGSAPPPRLASVLAFILEVLQRTQASELCDVELVLPAVLKCMVLVNELQVKKISTVIVQYMVQGCQARSGGEHATQLTSVFRQFIQDYTAVYDHRVFSILETVAVLDQTLVTSLIPTLTQSLKDSEYKQGLGRNAAQREAYKRLLTHLSEAGQNEIQKLENEAG

Gene
MMS22L
Protein
Protein MMS22-like
Organism
Gallus gallus
Length
1243 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks.
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
140.908 kDa
Sequence
MDSFTPPLLSDSLQMAMEVENEKSNPPCFSCIFDNQNGGRSFSGESYLASGSLKRVLLRLDPSPNDYEEDAIEMFGFQWVTETALVESCGLLFGLLRQQIYKLEDLIEMNSSDFGKAANLHSEAENIRRLCINFLHYVKVFIFRYLEPPKTENDGVLHPYEELEAQFPSLLVEELHSLTLHIGHLCELPSNVLAAFTIQHQAKIFPPSWHLLHLHLDIHWLVLEILHVLSEKMMRQVVYANHFINLTGENLTNISLFETHCENLISDLISLSIQKYTKVRPSEALTSHHYPCNCIKELWILLIQLLGFRNKGSQTECFWSLVNKKLKSIFERPTSSESVSVFGTTQCKDPLSFSLWIVTHLASLYQFDRNGNLEEKKQKESNWKFVEELLKNSIGAQTGVLEEHLRMHLQCCLTLCRFWDWNLSVITILWDYYSKNLNSCFTVPWLGLKGLASISKTSLSMLELVKSCCCEQQIPTLYKSSNSYLIFLSILARMMKEEAESSGVHPWKQIKGRIYSKFHRKRMQELTEVGLQNFFNLFLLLAIVAETEDIVSRVLDLLDFLTPSLVSPSQRALIWRGHFAFLLIYVEKNMDISVLAEKLSNAFRVKAKEFLVTKNDYTQKQNLWTLISTYIDGVQEVFETSCYLSLSEEKLLNDGFTMLLPACRGAELSMVLNFLQVVIARLRSVHKRVSQGLQPGNADSNAQLPLVAKEHHLAVASALWRNFFPYLKSQRMSQTPPSPQLADTAAGFALLALDIPSKALSDLQPQPVLSMMQLFGWDDMVWPHLVSRYLSHLIQNSALCEAFSTMGYTSYEALTVRSWFRCVLQMFIDQPSGTLAKTDAERTVGKAYMEQLTEMTRLIFKLKEVESILSKARVEEPVLKQDPKNALVQFIKAVGRTYSGLQTLPEKSAMVLKALEYLGDVLKYVKPYLKAKGPPEGLQLAYWIIGCLVKFWAPILATSKAQQLLFRIIDCLLLPHSVLQQDKELPGALLSAIQESLHLYLQGLSFICCQSQARGAYLNQLLGSIVQQYFGRFLPPSPTALGAGQHPMLTALCSSITVPQALRLRKTTLHVINEHYMQFKGSAPPPRLASVLAFILEVLQRTQASELCDVELVLPAVLKCMVLVNELQVKKISTVIVQYMVQGCQARSGGEHATQLTSVFRQFIQDYTAVYDHRVFSILETVAVLDQTLVTSLIPTLTQSLKDSEYKQGLGRNAAQREAYKRLLTHLSEAGQNEIQKLENEAG

Gene
MMS22L
Protein
Protein MMS22-like
Organism
Homo sapiens
Length
1243 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
142.321 kDa
Sequence
MENCSAASTFLTDSLELELGTEWCKPPYFSCAVDNRGGGKHFSGESYLCSGALKRLILNLDPLPTNFEEDTLEIFGIQWVTETALVNSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLHCKADNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDELHGLLLYIGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRKVESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCCDKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEVEDVASHVLDLLNFLKPAFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSHSGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKETNTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT

Gene
mms22l
Protein
Protein MMS22-like
Organism
Danio rerio
Length
1240 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks.
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
138.402 kDa
Sequence
MESEFSQSLTPPVSPSALNHYGESAPSRPPCFTCAYEAGREDTGRLSSNGYISRGALKRLLLKLDPAPADFGGDTVDIFDFPWVTETALVESTKLLFGLFRQKVLKLETLVQSSSHDFGQASSLHYEAEELRQQCVLFLSYIKVFIYRFLEPSQSLDEGPVHPFKDAEAQLPSVLVEELFSITLLIGRIGNLPANVQSAFTIQHQGKLFPPSWQLLHLHLDIHWSVLEILHLLEQRMMGQVVYAHQFVNLTGETLTNISLFEDQVNNLFCDLIGLAMNKYNKVRPTETLNTHHYHCLCTKELWILLIHLLEHRSKSIHTQSFWSYINALLQTVLKGTTSGDRDPGFPVHCKDPEGFTWWLLTHLAQIGMHNRNGTAQQEKQLEDNWSFVIGLLKSICDPKKAAQEEQIRVVVHCCLSLSLMWGPNVSAVTTFWEYYSKNLNSSFTVPWLGVSGLGSICRTPLCLLQQAKSCCSPAPVGSSSHTQLYRTANSFHIFLRILALHLSQEHAGGAPWRQIKGRLYSKFHQRRMMELSDMGLLHFLLLFLVLAQCAELEDVASRACDLLAMLPTNSTPLALRALQWRGQLALVLLYLEKGLDVGALAEQLAVYFSQAAREFYLKTTEPSRKLALWAPLSSYLEGVSEVFETSPNLTLSEERLLNEGFGLLLPACRQSELSSALGFLQTVLAQLRRVHQRCGQPSHSVDSPSWAPLPSVAKERHQAVAAALWSHFFPFLCSMRLSQTPPPQLADAAAGFTLLALDMPGSAPQNLQPHPIQSIMQSFGWDEMLHPLLVTHYLNHLLQNGELVSWVSSGQGSGSAQALCVRAWIRCVLQQYLHKSPDAPDARAGRNLDEQLAELTRQVFRLPEVEFVLQRAGLQSAAVKDPKAAMAVFLKAVGRSYCELQLLSERSSAVSRALEYVGDILKYIKPYLQNKSREGLQLAYWTIGCLVKHWSHLLATSKAQQLLFRIVDVLLLPHALLQQDTAAHTQMLSALKDSLPMFLQGLSVAVSVSHSQGAYLKQQQHSVISQYLSRFLPATPSTGAVVNHPVLLAACESTPSPQGERLRKSILHVLRENFLQFKGLAPPPRLAAVLCFLLELLKRNSDRDPALLTIPLPSVLRCLMLVNEPQVKRLSSEVTQLIVERCTAAVGEQPCEHTTAILRAFVDENEGVYDQQVYNVLEVVAVLHPFTVAALIPFLTLSLRKTECKRGLGKNTSLRNGYRRLLALLGDSGQAEMISLEED

Gene
Mms22l
Protein
Protein MMS22-like
Organism
Mus musculus
Length
1238 amino acids
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA (By similarity).
Similarity
Belongs to the MMS22 family. MMS22L subfamily.
Mass
140.582 kDa
Sequence
MDGCSAASTFLTDSLELELGTEWCKPPCFSCAFDNREGKFSGESYLASGALKRLILNLDPLPTNFEEDTVELFGFQWVTETALVYSCRELFHLFRQQIFNLESLVQVSCDFGKIATLHAKADSIRQQCVVFLHYIKVFIFRCLKVQEAESHSRPAHPYEALEAQLPSMLVDELRGLLLYIGHLAALPSVTVGAFVNQNQMKLFPPSWHLLHLYLDTHWLVLEILHILGEKLKQVVYGRQFIGQAGDNLTNVSLFEEHCEHLFCDLICLSLNRFDKVMPSEALLISHCPCSCVKELWVLLIHLLDHRRKWSVADSFWNWLNKLLRTLFEKSSDQRRSSVSLTQAKDPLGFSWWISVHVASLYQIDRHGVSDKMKQMESNWSFIEELLKRSVTVQDSILEEQLRMHLHCCLTLCDFWEPNISVVTILWEYYSKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVRNCCSDKQDPDLYKSSSSYIIFLCILAKVVKKAMRTSGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEIEDVASHVLDLLRFLRPASMSSHGALVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKNDEMVQRHALWTLLCIYIDGVQEVFETSSCLYPSHEHLLNDGFSMLLPACRESELRTVLNFLQAVLARIRSVHQQLCQELQRENVDLTVQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIIQLFGWDDIIWPQVVARYLSHLLQNSTVYEALSQSSCVSSQSLTIRSWVRCVLQMHIKHLSDPDLLIDVNPEQAVEKEYMEQLAEMTRLLFTLSEVKSVFSKAQIEQLPSPDDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEVLKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAHIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPGPMLTAIQKTLPLYLQGICIVCCQSQNPNAYLNQLLRNVIEQYIGRFLPTSPCVSDLGQHPVLLALRNPASVPSMTPLRKHTVHAIRKSYLEFKGSSPPPRLASVLAFVLQLFKDTEMGACDLELLLPGILKCLVLVNEPQVKKLATENLQCMVQTCQVGSEGGPATQLTSLFRQFIQDYGMQYSYQVYSILETVATLNQHVVIQLIPTLTQSLKDSELKWGLGRNIAQREAYSRLLSGLGQVGQGEKQRLEK