Protein
Short-chain Z-isoprenyl diphosphate synthase
Organism
Mycobacterium leprae (strain TN)
Function
Generates Z-farnesyl diphosphate (Z-FPP) from isopentenyl pyrophosphate (IPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall (By similarity).
Similarity
Belongs to the UPP synthase family. Z-FPP synthase subfamily.
Sequence
MEIIPPRLKEPLYALYELRLRQGLTASESRLPRHIAVLCDGNRRWARDAGYDDVSYGYRMGAAKIAEMLRWCQEAGIEMTTVYLLSTENLQRDPDELAALIEIITDVVEEICAPANRWSVRTVGDLELLGEEPACRLRGAVESTPGVAPFHVNVAVGYGGRREIVGAVRALLGKELANGATAEELVEAVTVEGIARNLYTSGQPDPDLVIRTSGEQRLSGFLLWQSAYSEMWFTETHWPAFRRVDFLRALRDYSMRHRRYGK