About Products Protein Database Contact

MKNK1

Gene
MKNK1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Homo sapiens
Length
465 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
51.342 kDa
Sequence
MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL

Gene
Mknk1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Mus musculus
Length
427 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
47.915 kDa
Sequence
MVSSQKLEKPIEMGSSEPLPIVDSDKRRKKKRKTRATDSLPGKFEDVYQLTSELLGEGAYAKVQGAVNLQSGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNEREASRVVRDVATALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEQEALAEGLCSMKLSPPSKSRLARRRALAQAGRSRDANPCLTPAGL

Gene
MKNK1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Bos taurus
Length
420 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
46.7 kDa
Sequence
MGSSEPIPIAESDKRKKKKRKARATDSLPGKFEDVYKLTSELLGEGANAKVQVAVSLQNGNEYAVKIIEKHAGHSRSRVFREVETLYQCQGNKHILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFRHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCTVCQNKLFESIQKGKYEFPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEQNKLAEESEVLAEGLCSVKLSPPSKSRLARRRALAQAGRSGDAPPSPTPTTPAP

Gene
mknk1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Xenopus laevis
Length
418 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
46.916 kDa
Sequence
MVSSQPVPFDDGGKRRKKKRKTRAMESFTGKFADLYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSRVFREVETLYQCQGNKNILELIEFCEDDARFYLVFEKLLGGSILSHIQKRKHFNEREASKVVKDIASALDFLHTKGIAHRDLKPENILCEFKDKVSPVKICDFDLGSGVKLNSACTTITTPELTTPCGSAEYMAPEVVEVFTEEATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGTDCGWDRGEVCRVCQNKLFESIQEGKYEFPEKDWSHISISAKDLISKLLVRDAKERLSAFQVLQHPWLQGDAPERGLPTPLVLQRNSSTKDLTIFAAEAIAFNRQLSQHDNDLNEEDESFIHAVCSMRLSPPSKSRLAKRRAQAHARKGGSHPTHSTVTASQGTP

Gene
mknk1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Xenopus tropicalis
Length
417 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
46.786 kDa
Sequence
MVSSQPVPIDDGGKRRKKKRRTRAMESFTGKFADLYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSRVFREVETLYQCQGNKNILELIEFCEDDARFYLVFEKLRGGSILSHIQKRKHFNEREASKVVKDIASALDFLHTKGIAHRDLKPENILCEFKDKVSPVKICDFDLGSGVKLNSACTPITTPELTTPCGSAEYMAPEVVEVFTEEATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGADCGWDRGEMCRVCQNKLFESIQEGKYEFPEKDWSHISNSAKDLISKLLVRDAKERLSAAQVLQHPWLQGDAPERGLPTPLVLQRNSSTKDLTIFAAEAVALNRQLSQHDSDLNEEHESFIHTVCSMRLSPPSKSRLAKRRAQAHARKGGSHLTHTTVTSQGAT

Gene
Mknk1
Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Rattus norvegicus
Length
413 amino acids
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Mass
46.214 kDa
Sequence
MGSSEPLPIVDSDKRRKKKRKTRATDSLPGKFEDVYQLTSELLGEGAYAKVQGAVSLQSGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNELEASRVVRDVATALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAHISTEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEHEALAEGLCSMKLSPPSKSRLARRRALAHAGREANSCSTPAGL