Protein
MAP kinase-interacting serine/threonine-protein kinase 1
Organism
Xenopus tropicalis
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Similarity
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Sequence
MVSSQPVPIDDGGKRRKKKRRTRAMESFTGKFADLYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSRVFREVETLYQCQGNKNILELIEFCEDDARFYLVFEKLRGGSILSHIQKRKHFNEREASKVVKDIASALDFLHTKGIAHRDLKPENILCEFKDKVSPVKICDFDLGSGVKLNSACTPITTPELTTPCGSAEYMAPEVVEVFTEEATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGADCGWDRGEMCRVCQNKLFESIQEGKYEFPEKDWSHISNSAKDLISKLLVRDAKERLSAAQVLQHPWLQGDAPERGLPTPLVLQRNSSTKDLTIFAAEAVALNRQLSQHDSDLNEEHESFIHTVCSMRLSPPSKSRLAKRRAQAHARKGGSHLTHTTVTSQGAT